LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T PI103
10.0
uM
LJP6
 72
hr
 929 1293 3228 0.4006 0.1582
Hs 578T PLX-4720
10.0
uM
LJP5
 72
hr
 929 2889 3228 0.8952 0.8528
Hs 578T QL-X-138
10.0
uM
LJP6
 72
hr
 929 980 3228 0.3036 0.0221
Hs 578T QL-XII-47
10.0
uM
LJP6
 72
hr
 929 822 3228 0.2546 -0.0467
Hs 578T Radicicol
10.0
uM
LJP5
 72
hr
 929 1307 3228 0.4050 0.1645
Hs 578T Radicicol
10.0
uM
LJP6
 72
hr
 929 1261 3228 0.3907 0.1445
Hs 578T Seliciclib
10.0
uM
LJP5
 72
hr
 929 2538 3228 0.7864 0.7001
Hs 578T Ruxolitinib
10.0
uM
LJP5
 72
hr
 929 2421 3228 0.7502 0.6492
Hs 578T XL147
10.0
uM
LJP5
 72
hr
 929 2805 3228 0.8689 0.8160
Hs 578T Saracatinib
10.0
uM
LJP6
 72
hr
 929 1622 3228 0.5026 0.3015
Hs 578T Selumetinib
10.0
uM
LJP6
 72
hr
 929 1501 3228 0.4650 0.2487
Hs 578T Sirolimus
10.0
uM
LJP6
 72
hr
 929 2276 3228 0.7052 0.5860
Hs 578T Sorafenib
10.0
uM
LJP6
 72
hr
 929 3036 3228 0.9406 0.9166
Hs 578T SU11274
10.0
uM
LJP5
 72
hr
 929 1371 3228 0.4247 0.1922
Hs 578T Fedratinib
10.0
uM
LJP5
 72
hr
 929 921 3228 0.2853 -0.0036
Hs 578T TGX221
10.0
uM
LJP5
 72
hr
 929 2401 3228 0.7439 0.6404
Hs 578T Torin1
10.0
uM
LJP6
 72
hr
 929 1031 3228 0.3195 0.0444
Hs 578T Torin2
10.0
uM
LJP5
 72
hr
 929 949 3228 0.2942 0.0089
Hs 578T Tozasertib
10.0
uM
LJP5
 72
hr
 929 1127 3228 0.3493 0.0863
Hs 578T Trametinib
10.0
uM
LJP5
 72
hr
 929 1497 3228 0.4640 0.2473
Hs 578T TWS119
10.0
uM
LJP5
 72
hr
 929 1000 3228 0.3099 0.0309
Hs 578T Vemurafenib
10.0
uM
LJP5
 72
hr
 929 2051 3228 0.6355 0.4881
Hs 578T Withaferin A
10.0
uM
LJP5
 72
hr
 929 558 3228 0.1729 -0.1615
Hs 578T Withaferin A
10.0
uM
LJP6
 72
hr
 929 411 3228 0.1274 -0.2253
Hs 578T WYE-125132
10.0
uM
LJP6
 72
hr
 929 1265 3228 0.3920 0.1462