LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T WZ3105
10.0
uM
LJP5
 72
hr
 929 913 3228 0.2830 -0.0068
Hs 578T XMD11-50
10.0
uM
LJP6
 72
hr
 929 962 3228 0.2980 0.0142
Hs 578T Y39983
10.0
uM
LJP6
 72
hr
 929 1211 3228 0.3752 0.1226
Hs 578T YM 201636
10.0
uM
LJP5
 72
hr
 929 1272 3228 0.3942 0.1493
Hs 578T ZSTK474
10.0
uM
LJP6
 72
hr
 929 1256 3228 0.3891 0.1421
MCF 10A Afatinib
0.04
uM
LJP6
 72
hr
 513 351 10401 0.0338 -0.0164
MCF 10A Sigma A6730
0.04
uM
LJP5
 72
hr
 513 9985 10401 0.9600 0.9580
MCF 10A Alvocidib
0.04
uM
LJP6
 72
hr
 513 1211 10401 0.1165 0.0706
MCF 10A AT-7519
0.04
uM
LJP6
 72
hr
 513 9912 10401 0.9530 0.9505
MCF 10A AZD 5438
0.04
uM
LJP6
 72
hr
 513 9444 10401 0.9080 0.9033
MCF 10A AZD-6482
0.04
uM
LJP5
 72
hr
 513 9739 10401 0.9364 0.9331
MCF 10A AZD7762
0.04
uM
LJP6
 72
hr
 513 6866 10401 0.6602 0.6425
MCF 10A AZD8055
0.04
uM
LJP6
 72
hr
 513 2503 10401 0.2407 0.2013
MCF 10A AZD8330
0.04
uM
LJP5
 72
hr
 513 447 10401 0.0430 -0.0067
MCF 10A Barasertib
0.04
uM
LJP5
 72
hr
 513 1407 10401 0.1353 0.0904
MCF 10A BI-2536
0.04
uM
LJP6
 72
hr
 513 739 10401 0.0711 0.0228
MCF 10A BMS345541
0.04
uM
LJP6
 72
hr
 513 10692 10401 1.0280 1.0294
MCF 10A SNS-032
0.04
uM
LJP6
 72
hr
 513 6891 10401 0.6625 0.6450
MCF 10A GDC-0980
0.04
uM
LJP5
 72
hr
 513 5062 10401 0.4867 0.4601
MCF 10A NVP-AEW541
0.04
uM
LJP5
 72
hr
 513 9731 10401 0.9356 0.9322
MCF 10A SB590885
0.04
uM
LJP5
 72
hr
 513 10835 10401 1.0417 1.0439
MCF 10A PIK-93
0.04
uM
LJP5
 72
hr
 513 10310 10401 0.9913 0.9908
MCF 10A KIN001-043
0.04
uM
LJP6
 72
hr
 513 11127 10401 1.0698 1.0734
MCF 10A Alpelisib
0.04
uM
LJP5
 72
hr
 513 9455 10401 0.9090 0.9043
MCF 10A Luminespib
0.04
uM
LJP5
 72
hr
 513 474 10401 0.0456 -0.0040