LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T BI-2536
0.04
uM
LJP6
 72
hr
 929 899 3228 0.2787 -0.0129
Hs 578T BMS345541
0.04
uM
LJP6
 72
hr
 929 3254 3228 1.0082 1.0116
Hs 578T SNS-032
0.04
uM
LJP6
 72
hr
 929 2686 3228 0.8321 0.7642
Hs 578T GDC-0980
0.04
uM
LJP5
 72
hr
 929 2406 3228 0.7454 0.6425
Hs 578T NVP-AEW541
0.04
uM
LJP5
 72
hr
 929 3371 3228 1.0444 1.0623
Hs 578T SB590885
0.04
uM
LJP5
 72
hr
 929 3913 3228 1.2123 1.2981
Hs 578T PIK-93
0.04
uM
LJP5
 72
hr
 929 3293 3228 1.0203 1.0285
Hs 578T KIN001-043
0.04
uM
LJP6
 72
hr
 929 3342 3228 1.0353 1.0496
Hs 578T Alpelisib
0.04
uM
LJP5
 72
hr
 929 3166 3228 0.9808 0.9730
Hs 578T Luminespib
0.04
uM
LJP5
 72
hr
 929 1342 3228 0.4157 0.1796
Hs 578T A443654
0.04
uM
LJP6
 72
hr
 929 2096 3228 0.6494 0.5077
Hs 578T OSI-027
0.04
uM
LJP6
 72
hr
 929 3225 3228 0.9991 0.9987
Hs 578T XMD11-85h
0.04
uM
LJP6
 72
hr
 929 3182 3228 0.9857 0.9800
Hs 578T HG-6-64-01
0.04
uM
LJP6
 72
hr
 929 3750 3228 1.1619 1.2273
Hs 578T WH-4-025
0.04
uM
LJP5
 72
hr
 929 3269 3228 1.0128 1.0180
Hs 578T WZ-4-145
0.04
uM
LJP6
 72
hr
 929 2380 3228 0.7373 0.6311
Hs 578T XMD16-144
0.04
uM
LJP5
 72
hr
 929 1812 3228 0.5614 0.3842
Hs 578T Brivanib
0.04
uM
LJP5
 72
hr
 929 3078 3228 0.9535 0.9347
Hs 578T Buparlisib
0.04
uM
LJP5
 72
hr
 929 3189 3228 0.9881 0.9833
Hs 578T BX-912
0.04
uM
LJP5
 72
hr
 929 3149 3228 0.9757 0.9659
Hs 578T Canertinib
0.04
uM
LJP6
 72
hr
 929 3209 3228 0.9943 0.9920
Hs 578T Celastrol
0.04
uM
LJP6
 72
hr
 929 3393 3228 1.0511 1.0717
Hs 578T CGP60474
0.04
uM
LJP5
 72
hr
 929 3045 3228 0.9433 0.9204
Hs 578T CGP60474
0.04
uM
LJP6
 72
hr
 929 818 3228 0.2535 -0.0482
Hs 578T CHIR-99021
0.04
uM
LJP6
 72
hr
 929 3117 3228 0.9657 0.9518