LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Canertinib
3.33
uM
LJP6
 72
hr
 868 2305 3486 0.6611 0.5488
MDA-MB-231 Celastrol
3.33
uM
LJP6
 72
hr
 868 692 3486 0.1986 -0.0671
MDA-MB-231 CGP60474
3.33
uM
LJP5
 72
hr
 868 631 3486 0.1812 -0.0903
MDA-MB-231 CGP60474
3.33
uM
LJP6
 72
hr
 868 527 3486 0.1512 -0.1303
MDA-MB-231 CHIR-99021
3.33
uM
LJP6
 72
hr
 868 2911 3486 0.8352 0.7805
MDA-MB-231 CP724714
3.33
uM
LJP5
 72
hr
 868 2362 3486 0.6777 0.5708
MDA-MB-231 CP466722
3.33
uM
LJP5
 72
hr
 868 3398 3486 0.9747 0.9664
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 72
hr
 868 1133 3486 0.3251 0.1013
MDA-MB-231 Momelotinib
3.33
uM
LJP5
 72
hr
 868 2047 3486 0.5872 0.4504
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 72
hr
 868 515 3486 0.1477 -0.1349
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 72
hr
 868 460 3486 0.1320 -0.1558
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 72
hr
 868 1649 3486 0.4731 0.2984
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 72
hr
 868 3483 3486 0.9990 0.9987
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 72
hr
 868 3356 3486 0.9626 0.9502
MDA-MB-231 Foretinib
3.33
uM
LJP5
 72
hr
 868 1389 3486 0.3984 0.1989
MDA-MB-231 R406
3.33
uM
LJP6
 72
hr
 868 2438 3486 0.6995 0.5998
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 72
hr
 868 2550 3486 0.7316 0.6426
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 72
hr
 868 3848 3486 1.1037 1.1381
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 72
hr
 868 859 3486 0.2465 -0.0034
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 72
hr
 868 964 3486 0.2766 0.0367
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 72
hr
 868 781 3486 0.2240 -0.0333
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 72
hr
 868 1178 3486 0.3381 0.1186
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 72
hr
 868 3396 3486 0.9742 0.9656
MDA-MB-231 Omipalisib
3.33
uM
LJP6
 72
hr
 868 1030 3486 0.2954 0.0618
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 72
hr
 868 3459 3486 0.9923 0.9898