LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 JW-7-24-1
0.37
uM
LJP6
 72
hr
 868 2426 3486 0.6959 0.5950
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 72
hr
 868 3351 3486 0.9614 0.9485
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 72
hr
 868 3428 3486 0.9834 0.9778
MDA-MB-231 Linifanib
0.37
uM
LJP6
 72
hr
 868 4037 3486 1.1580 1.2104
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 72
hr
 868 2875 3486 0.8246 0.7665
MDA-MB-231 Mitoxantrone
0.37
uM
LJP5
 72
hr
 868 810 3486 0.2325 -0.0219
MDA-MB-231 Mitoxantrone
0.37
uM
LJP6
 72
hr
 868 827 3486 0.2374 -0.0155
MDA-MB-231 MK2206
0.37
uM
LJP6
 72
hr
 868 2762 3486 0.7923 0.7235
MDA-MB-231 Neratinib
0.37
uM
LJP5
 72
hr
 868 2194 3486 0.6293 0.5064
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 72
hr
 868 2617 3486 0.7506 0.6680
MDA-MB-231 Nintedanib
0.37
uM
LJP6
 72
hr
 868 3503 3486 1.0049 1.0065
MDA-MB-231 NU7441
0.37
uM
LJP5
 72
hr
 868 2800 3486 0.8032 0.7380
MDA-MB-231 Dactolisib
0.37
uM
LJP5
 72
hr
 868 1589 3486 0.4559 0.2755
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 72
hr
 868 2590 3486 0.7430 0.6578
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 72
hr
 868 1974 3486 0.5664 0.4226
MDA-MB-231 PD0325901
0.37
uM
LJP5
 72
hr
 868 1473 3486 0.4225 0.2310
MDA-MB-231 PD0325901
0.37
uM
LJP6
 72
hr
 868 1384 3486 0.3972 0.1973
MDA-MB-231 PD173074
0.37
uM
LJP6
 72
hr
 868 3593 3486 1.0306 1.0407
MDA-MB-231 PD184352
0.37
uM
LJP5
 72
hr
 868 2608 3486 0.7481 0.6645
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 72
hr
 868 2867 3486 0.8225 0.7637
MDA-MB-231 PF431396
0.37
uM
LJP5
 72
hr
 868 2233 3486 0.6405 0.5213
MDA-MB-231 PF477736
0.37
uM
LJP5
 72
hr
 868 2622 3486 0.7521 0.6699
MDA-MB-231 PF562271
0.37
uM
LJP6
 72
hr
 868 2810 3486 0.8061 0.7418
MDA-MB-231 PHA-665752
0.37
uM
LJP5
 72
hr
 868 3640 3486 1.0441 1.0587
MDA-MB-231 PHA-793887
0.37
uM
LJP6
 72
hr
 868 985 3486 0.2827 0.0449