LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PIK-93 | 10.0 | uM | LJP5 | 3 | K13 | 72 | hr | 1401 | 1389 | 4223 | 0.3289 | -0.0044 |
| SK-BR-3 | KIN001-043 | 10.0 | uM | LJP6 | 1 | C07 | 72 | hr | 1401 | 2496 | 4223 | 0.5910 | 0.3879 |
| SK-BR-3 | KIN001-043 | 10.0 | uM | LJP6 | 2 | C07 | 72 | hr | 1401 | 2307 | 4223 | 0.5463 | 0.3209 |
| SK-BR-3 | KIN001-043 | 10.0 | uM | LJP6 | 3 | C07 | 72 | hr | 1401 | 2285 | 4223 | 0.5411 | 0.3131 |
| SK-BR-3 | Alpelisib | 10.0 | uM | LJP5 | 1 | N01 | 72 | hr | 1401 | 1436 | 4223 | 0.3400 | 0.0122 |
| SK-BR-3 | Alpelisib | 10.0 | uM | LJP5 | 2 | N01 | 72 | hr | 1401 | 1729 | 4223 | 0.4094 | 0.1161 |
| SK-BR-3 | Alpelisib | 10.0 | uM | LJP5 | 3 | N01 | 72 | hr | 1401 | 1616 | 4223 | 0.3827 | 0.0760 |
| SK-BR-3 | Luminespib | 10.0 | uM | LJP5 | 1 | H13 | 72 | hr | 1401 | 1510 | 4223 | 0.3576 | 0.0384 |
| SK-BR-3 | Luminespib | 10.0 | uM | LJP5 | 2 | H13 | 72 | hr | 1401 | 1584 | 4223 | 0.3751 | 0.0647 |
| SK-BR-3 | Luminespib | 10.0 | uM | LJP5 | 3 | H13 | 72 | hr | 1401 | 1619 | 4223 | 0.3834 | 0.0771 |
| SK-BR-3 | A443654 | 10.0 | uM | LJP6 | 1 | I19 | 72 | hr | 1401 | 932 | 4223 | 0.2207 | -0.1664 |
| SK-BR-3 | A443654 | 10.0 | uM | LJP6 | 2 | I19 | 72 | hr | 1401 | 823 | 4223 | 0.1949 | -0.2050 |
| SK-BR-3 | A443654 | 10.0 | uM | LJP6 | 3 | I19 | 72 | hr | 1401 | 1040 | 4223 | 0.2463 | -0.1281 |
| SK-BR-3 | OSI-027 | 10.0 | uM | LJP6 | 1 | E07 | 72 | hr | 1401 | 1639 | 4223 | 0.3881 | 0.0842 |
| SK-BR-3 | OSI-027 | 10.0 | uM | LJP6 | 2 | E07 | 72 | hr | 1401 | 1674 | 4223 | 0.3964 | 0.0966 |
| SK-BR-3 | OSI-027 | 10.0 | uM | LJP6 | 3 | E07 | 72 | hr | 1401 | 1663 | 4223 | 0.3938 | 0.0927 |
| SK-BR-3 | XMD11-85h | 10.0 | uM | LJP6 | 1 | P19 | 72 | hr | 1401 | 3319 | 4223 | 0.7859 | 0.6796 |
| SK-BR-3 | XMD11-85h | 10.0 | uM | LJP6 | 2 | P19 | 72 | hr | 1401 | 3207 | 4223 | 0.7594 | 0.6399 |
| SK-BR-3 | XMD11-85h | 10.0 | uM | LJP6 | 3 | P19 | 72 | hr | 1401 | 3205 | 4223 | 0.7589 | 0.6392 |
| SK-BR-3 | HG-6-64-01 | 10.0 | uM | LJP6 | 1 | M01 | 72 | hr | 1401 | 369 | 4223 | 0.0874 | -0.3659 |
| SK-BR-3 | HG-6-64-01 | 10.0 | uM | LJP6 | 2 | M01 | 72 | hr | 1401 | 631 | 4223 | 0.1494 | -0.2731 |
| SK-BR-3 | HG-6-64-01 | 10.0 | uM | LJP6 | 3 | M01 | 72 | hr | 1401 | 548 | 4223 | 0.1298 | -0.3025 |
| SK-BR-3 | WH-4-025 | 10.0 | uM | LJP5 | 1 | O07 | 72 | hr | 1401 | 1316 | 4223 | 0.3116 | -0.0303 |
| SK-BR-3 | WH-4-025 | 10.0 | uM | LJP5 | 2 | O07 | 72 | hr | 1401 | 1203 | 4223 | 0.2849 | -0.0704 |
| SK-BR-3 | WH-4-025 | 10.0 | uM | LJP5 | 3 | O07 | 72 | hr | 1401 | 1026 | 4223 | 0.2430 | -0.1331 |