LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 TGX221
10.0
uM
LJP5
1
H19
72
hr
1401 3726 4223 0.8823 0.8238
SK-BR-3 TGX221
10.0
uM
LJP5
2
H19
72
hr
1401 3787 4223 0.8967 0.8454
SK-BR-3 TGX221
10.0
uM
LJP5
3
H19
72
hr
1401 3884 4223 0.9197 0.8798
SK-BR-3 Torin1
10.0
uM
LJP6
1
O13
72
hr
1401 1396 4223 0.3306 -0.0020
SK-BR-3 Torin1
10.0
uM
LJP6
2
O13
72
hr
1401 1316 4223 0.3116 -0.0303
SK-BR-3 Torin1
10.0
uM
LJP6
3
O13
72
hr
1401 1208 4223 0.2861 -0.0686
SK-BR-3 Torin2
10.0
uM
LJP5
1
I19
72
hr
1401 938 4223 0.2221 -0.1643
SK-BR-3 Torin2
10.0
uM
LJP5
2
I19
72
hr
1401 958 4223 0.2269 -0.1572
SK-BR-3 Torin2
10.0
uM
LJP5
3
I19
72
hr
1401 1246 4223 0.2950 -0.0551
SK-BR-3 Tozasertib
10.0
uM
LJP5
1
B13
72
hr
1401 1503 4223 0.3559 0.0360
SK-BR-3 Tozasertib
10.0
uM
LJP5
2
B13
72
hr
1401 1644 4223 0.3893 0.0859
SK-BR-3 Tozasertib
10.0
uM
LJP5
3
B13
72
hr
1401 1541 4223 0.3649 0.0494
SK-BR-3 Trametinib
10.0
uM
LJP5
1
P19
72
hr
1401 3293 4223 0.7798 0.6704
SK-BR-3 Trametinib
10.0
uM
LJP5
2
P19
72
hr
1401 3536 4223 0.8373 0.7565
SK-BR-3 Trametinib
10.0
uM
LJP5
3
P19
72
hr
1401 4014 4223 0.9505 0.9259
SK-BR-3 TWS119
10.0
uM
LJP5
1
M01
72
hr
1401 847 4223 0.2006 -0.1965
SK-BR-3 TWS119
10.0
uM
LJP5
2
M01
72
hr
1401 1614 4223 0.3822 0.0753
SK-BR-3 TWS119
10.0
uM
LJP5
3
M01
72
hr
1401 2121 4223 0.5022 0.2550
SK-BR-3 Vemurafenib
10.0
uM
LJP5
1
C13
72
hr
1401 3922 4223 0.9287 0.8933
SK-BR-3 Vemurafenib
10.0
uM
LJP5
2
C13
72
hr
1401 3668 4223 0.8686 0.8033
SK-BR-3 Vemurafenib
10.0
uM
LJP5
3
C13
72
hr
1401 3192 4223 0.7558 0.6346
SK-BR-3 Withaferin A
10.0
uM
LJP5
1
G13
72
hr
1401 1080 4223 0.2557 -0.1140
SK-BR-3 Withaferin A
10.0
uM
LJP5
2
G13
72
hr
1401 1006 4223 0.2382 -0.1402
SK-BR-3 Withaferin A
10.0
uM
LJP5
3
G13
72
hr
1401 968 4223 0.2292 -0.1537
SK-BR-3 Withaferin A
10.0
uM
LJP6
1
G13
72
hr
1401 1261 4223 0.2986 -0.0498