LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SK-BR-3 | AZD8330 | 10.0 | uM | LJP5 | 2 | G19 | 72 | hr | 1401 | 3846 | 4223 | 0.9107 | 0.8664 |
SK-BR-3 | AZD8330 | 10.0 | uM | LJP5 | 3 | G19 | 72 | hr | 1401 | 4295 | 4223 | 1.0170 | 1.0255 |
SK-BR-3 | Barasertib | 10.0 | uM | LJP5 | 1 | D07 | 72 | hr | 1401 | 1402 | 4223 | 0.3320 | 0.0002 |
SK-BR-3 | Barasertib | 10.0 | uM | LJP5 | 2 | D07 | 72 | hr | 1401 | 1466 | 4223 | 0.3471 | 0.0229 |
SK-BR-3 | Barasertib | 10.0 | uM | LJP5 | 3 | D07 | 72 | hr | 1401 | 1412 | 4223 | 0.3344 | 0.0037 |
SK-BR-3 | BI-2536 | 10.0 | uM | LJP6 | 1 | D13 | 72 | hr | 1401 | 1400 | 4223 | 0.3315 | -0.0005 |
SK-BR-3 | BI-2536 | 10.0 | uM | LJP6 | 2 | D13 | 72 | hr | 1401 | 971 | 4223 | 0.2299 | -0.1526 |
SK-BR-3 | BI-2536 | 10.0 | uM | LJP6 | 3 | D13 | 72 | hr | 1401 | 1255 | 4223 | 0.2972 | -0.0519 |
SK-BR-3 | BMS345541 | 10.0 | uM | LJP6 | 1 | D01 | 72 | hr | 1401 | 694 | 4223 | 0.1643 | -0.2508 |
SK-BR-3 | BMS345541 | 10.0 | uM | LJP6 | 2 | D01 | 72 | hr | 1401 | 771 | 4223 | 0.1826 | -0.2235 |
SK-BR-3 | BMS345541 | 10.0 | uM | LJP6 | 3 | D01 | 72 | hr | 1401 | 835 | 4223 | 0.1977 | -0.2008 |
SK-BR-3 | SNS-032 | 10.0 | uM | LJP6 | 1 | H13 | 72 | hr | 1401 | 941 | 4223 | 0.2228 | -0.1632 |
SK-BR-3 | SNS-032 | 10.0 | uM | LJP6 | 2 | H13 | 72 | hr | 1401 | 1061 | 4223 | 0.2512 | -0.1207 |
SK-BR-3 | SNS-032 | 10.0 | uM | LJP6 | 3 | H13 | 72 | hr | 1401 | 1203 | 4223 | 0.2849 | -0.0704 |
SK-BR-3 | GDC-0980 | 10.0 | uM | LJP5 | 1 | K19 | 72 | hr | 1401 | 1281 | 4223 | 0.3033 | -0.0427 |
SK-BR-3 | GDC-0980 | 10.0 | uM | LJP5 | 2 | K19 | 72 | hr | 1401 | 1284 | 4223 | 0.3040 | -0.0417 |
SK-BR-3 | GDC-0980 | 10.0 | uM | LJP5 | 3 | K19 | 72 | hr | 1401 | 1252 | 4223 | 0.2965 | -0.0530 |
SK-BR-3 | NVP-AEW541 | 10.0 | uM | LJP5 | 1 | E13 | 72 | hr | 1401 | 2421 | 4223 | 0.5733 | 0.3613 |
SK-BR-3 | NVP-AEW541 | 10.0 | uM | LJP5 | 2 | E13 | 72 | hr | 1401 | 2518 | 4223 | 0.5963 | 0.3957 |
SK-BR-3 | NVP-AEW541 | 10.0 | uM | LJP5 | 3 | E13 | 72 | hr | 1401 | 2365 | 4223 | 0.5600 | 0.3415 |
SK-BR-3 | SB590885 | 10.0 | uM | LJP5 | 1 | L13 | 72 | hr | 1401 | 918 | 4223 | 0.2174 | -0.1714 |
SK-BR-3 | SB590885 | 10.0 | uM | LJP5 | 2 | L13 | 72 | hr | 1401 | 776 | 4223 | 0.1838 | -0.2217 |
SK-BR-3 | SB590885 | 10.0 | uM | LJP5 | 3 | L13 | 72 | hr | 1401 | 827 | 4223 | 0.1958 | -0.2036 |
SK-BR-3 | PIK-93 | 10.0 | uM | LJP5 | 1 | K13 | 72 | hr | 1401 | 1557 | 4223 | 0.3687 | 0.0551 |
SK-BR-3 | PIK-93 | 10.0 | uM | LJP5 | 2 | K13 | 72 | hr | 1401 | 1528 | 4223 | 0.3618 | 0.0448 |