LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Afatinib | 10.0 | uM | LJP6 | 1 | G19 | 72 | hr | 1401 | 1221 | 4223 | 0.2891 | -0.0640 |
| SK-BR-3 | Afatinib | 10.0 | uM | LJP6 | 2 | G19 | 72 | hr | 1401 | 1210 | 4223 | 0.2865 | -0.0679 |
| SK-BR-3 | Afatinib | 10.0 | uM | LJP6 | 3 | G19 | 72 | hr | 1401 | 1239 | 4223 | 0.2934 | -0.0576 |
| SK-BR-3 | Sigma A6730 | 10.0 | uM | LJP5 | 1 | B19 | 72 | hr | 1401 | 2069 | 4223 | 0.4899 | 0.2366 |
| SK-BR-3 | Sigma A6730 | 10.0 | uM | LJP5 | 2 | B19 | 72 | hr | 1401 | 2246 | 4223 | 0.5318 | 0.2993 |
| SK-BR-3 | Sigma A6730 | 10.0 | uM | LJP5 | 3 | B19 | 72 | hr | 1401 | 2464 | 4223 | 0.5835 | 0.3766 |
| SK-BR-3 | Alvocidib | 10.0 | uM | LJP6 | 1 | A13 | 72 | hr | 1401 | 1087 | 4223 | 0.2574 | -0.1115 |
| SK-BR-3 | Alvocidib | 10.0 | uM | LJP6 | 2 | A13 | 72 | hr | 1401 | 896 | 4223 | 0.2122 | -0.1792 |
| SK-BR-3 | Alvocidib | 10.0 | uM | LJP6 | 3 | A13 | 72 | hr | 1401 | 929 | 4223 | 0.2200 | -0.1675 |
| SK-BR-3 | AT-7519 | 10.0 | uM | LJP6 | 1 | K01 | 72 | hr | 1401 | 349 | 4223 | 0.0826 | -0.3730 |
| SK-BR-3 | AT-7519 | 10.0 | uM | LJP6 | 2 | K01 | 72 | hr | 1401 | 603 | 4223 | 0.1428 | -0.2830 |
| SK-BR-3 | AT-7519 | 10.0 | uM | LJP6 | 3 | K01 | 72 | hr | 1401 | 506 | 4223 | 0.1198 | -0.3174 |
| SK-BR-3 | AZD 5438 | 10.0 | uM | LJP6 | 1 | J01 | 72 | hr | 1401 | 827 | 4223 | 0.1958 | -0.2036 |
| SK-BR-3 | AZD 5438 | 10.0 | uM | LJP6 | 2 | J01 | 72 | hr | 1401 | 752 | 4223 | 0.1781 | -0.2302 |
| SK-BR-3 | AZD 5438 | 10.0 | uM | LJP6 | 3 | J01 | 72 | hr | 1401 | 800 | 4223 | 0.1894 | -0.2132 |
| SK-BR-3 | AZD-6482 | 10.0 | uM | LJP5 | 1 | I01 | 72 | hr | 1401 | 1129 | 4223 | 0.2673 | -0.0966 |
| SK-BR-3 | AZD-6482 | 10.0 | uM | LJP5 | 2 | I01 | 72 | hr | 1401 | 1973 | 4223 | 0.4672 | 0.2025 |
| SK-BR-3 | AZD-6482 | 10.0 | uM | LJP5 | 3 | I01 | 72 | hr | 1401 | 2028 | 4223 | 0.4802 | 0.2220 |
| SK-BR-3 | AZD7762 | 10.0 | uM | LJP6 | 1 | L01 | 72 | hr | 1401 | 807 | 4223 | 0.1911 | -0.2107 |
| SK-BR-3 | AZD7762 | 10.0 | uM | LJP6 | 2 | L01 | 72 | hr | 1401 | 947 | 4223 | 0.2242 | -0.1611 |
| SK-BR-3 | AZD7762 | 10.0 | uM | LJP6 | 3 | L01 | 72 | hr | 1401 | 814 | 4223 | 0.1928 | -0.2082 |
| SK-BR-3 | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 1401 | 429 | 4223 | 0.1016 | -0.3447 |
| SK-BR-3 | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 1401 | 438 | 4223 | 0.1037 | -0.3415 |
| SK-BR-3 | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 1401 | 463 | 4223 | 0.1096 | -0.3326 |
| SK-BR-3 | AZD8330 | 10.0 | uM | LJP5 | 1 | G19 | 72 | hr | 1401 | 3639 | 4223 | 0.8617 | 0.7930 |