LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 1 | M10 | 72 | hr | 1401 | 4556 | 4223 | 1.0788 | 1.1180 |
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 2 | M10 | 72 | hr | 1401 | 4038 | 4223 | 0.9562 | 0.9344 |
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 3 | M10 | 72 | hr | 1401 | 4437 | 4223 | 1.0507 | 1.0758 |
| SK-BR-3 | Sirolimus | 0.37 | uM | LJP6 | 1 | L16 | 72 | hr | 1401 | 2792 | 4223 | 0.6611 | 0.4928 |
| SK-BR-3 | Sirolimus | 0.37 | uM | LJP6 | 2 | L16 | 72 | hr | 1401 | 2645 | 4223 | 0.6263 | 0.4407 |
| SK-BR-3 | Sirolimus | 0.37 | uM | LJP6 | 3 | L16 | 72 | hr | 1401 | 2922 | 4223 | 0.6919 | 0.5389 |
| SK-BR-3 | Sorafenib | 0.37 | uM | LJP6 | 1 | B10 | 72 | hr | 1401 | 4259 | 4223 | 1.0085 | 1.0127 |
| SK-BR-3 | Sorafenib | 0.37 | uM | LJP6 | 2 | B10 | 72 | hr | 1401 | 4237 | 4223 | 1.0033 | 1.0049 |
| SK-BR-3 | Sorafenib | 0.37 | uM | LJP6 | 3 | B10 | 72 | hr | 1401 | 4074 | 4223 | 0.9647 | 0.9472 |
| SK-BR-3 | SU11274 | 0.37 | uM | LJP5 | 1 | J10 | 72 | hr | 1401 | 4298 | 4223 | 1.0177 | 1.0265 |
| SK-BR-3 | SU11274 | 0.37 | uM | LJP5 | 2 | J10 | 72 | hr | 1401 | 4276 | 4223 | 1.0125 | 1.0188 |
| SK-BR-3 | SU11274 | 0.37 | uM | LJP5 | 3 | J10 | 72 | hr | 1401 | 4885 | 4223 | 1.1567 | 1.2346 |
| SK-BR-3 | Fedratinib | 0.37 | uM | LJP5 | 1 | L04 | 72 | hr | 1401 | 3601 | 4223 | 0.8527 | 0.7795 |
| SK-BR-3 | Fedratinib | 0.37 | uM | LJP5 | 2 | L04 | 72 | hr | 1401 | 3982 | 4223 | 0.9429 | 0.9146 |
| SK-BR-3 | Fedratinib | 0.37 | uM | LJP5 | 3 | L04 | 72 | hr | 1401 | 4027 | 4223 | 0.9536 | 0.9305 |
| SK-BR-3 | TGX221 | 0.37 | uM | LJP5 | 1 | H22 | 72 | hr | 1401 | 3707 | 4223 | 0.8778 | 0.8171 |
| SK-BR-3 | TGX221 | 0.37 | uM | LJP5 | 2 | H22 | 72 | hr | 1401 | 4097 | 4223 | 0.9701 | 0.9553 |
| SK-BR-3 | TGX221 | 0.37 | uM | LJP5 | 3 | H22 | 72 | hr | 1401 | 4376 | 4223 | 1.0362 | 1.0542 |
| SK-BR-3 | Torin1 | 0.37 | uM | LJP6 | 1 | O16 | 72 | hr | 1401 | 1499 | 4223 | 0.3550 | 0.0345 |
| SK-BR-3 | Torin1 | 0.37 | uM | LJP6 | 2 | O16 | 72 | hr | 1401 | 1600 | 4223 | 0.3789 | 0.0703 |
| SK-BR-3 | Torin1 | 0.37 | uM | LJP6 | 3 | O16 | 72 | hr | 1401 | 1509 | 4223 | 0.3573 | 0.0381 |
| SK-BR-3 | Torin2 | 0.37 | uM | LJP5 | 1 | I22 | 72 | hr | 1401 | 1071 | 4223 | 0.2536 | -0.1171 |
| SK-BR-3 | Torin2 | 0.37 | uM | LJP5 | 2 | I22 | 72 | hr | 1401 | 1392 | 4223 | 0.3296 | -0.0034 |
| SK-BR-3 | Torin2 | 0.37 | uM | LJP5 | 3 | I22 | 72 | hr | 1401 | 1263 | 4223 | 0.2991 | -0.0491 |
| SK-BR-3 | Tozasertib | 0.37 | uM | LJP5 | 1 | B16 | 72 | hr | 1401 | 1363 | 4223 | 0.3228 | -0.0137 |