LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 BMS345541
0.37
uM
LJP6
3
D04
72
hr
1401 3936 4223 0.9320 0.8983
SK-BR-3 SNS-032
0.37
uM
LJP6
1
H16
72
hr
1401 1085 4223 0.2569 -0.1122
SK-BR-3 SNS-032
0.37
uM
LJP6
2
H16
72
hr
1401 1139 4223 0.2697 -0.0930
SK-BR-3 SNS-032
0.37
uM
LJP6
3
H16
72
hr
1401 1141 4223 0.2702 -0.0923
SK-BR-3 GDC-0980
0.37
uM
LJP5
1
K22
72
hr
1401 1261 4223 0.2986 -0.0498
SK-BR-3 GDC-0980
0.37
uM
LJP5
2
K22
72
hr
1401 1342 4223 0.3178 -0.0211
SK-BR-3 GDC-0980
0.37
uM
LJP5
3
K22
72
hr
1401 1626 4223 0.3850 0.0796
SK-BR-3 NVP-AEW541
0.37
uM
LJP5
1
E16
72
hr
1401 3551 4223 0.8409 0.7618
SK-BR-3 NVP-AEW541
0.37
uM
LJP5
2
E16
72
hr
1401 3791 4223 0.8977 0.8469
SK-BR-3 NVP-AEW541
0.37
uM
LJP5
3
E16
72
hr
1401 3992 4223 0.9453 0.9181
SK-BR-3 SB590885
0.37
uM
LJP5
1
L16
72
hr
1401 4537 4223 1.0743 1.1113
SK-BR-3 SB590885
0.37
uM
LJP5
2
L16
72
hr
1401 4587 4223 1.0862 1.1290
SK-BR-3 SB590885
0.37
uM
LJP5
3
L16
72
hr
1401 4932 4223 1.1679 1.2512
SK-BR-3 PIK-93
0.37
uM
LJP5
1
K16
72
hr
1401 3878 4223 0.9183 0.8777
SK-BR-3 PIK-93
0.37
uM
LJP5
2
K16
72
hr
1401 4203 4223 0.9952 0.9929
SK-BR-3 PIK-93
0.37
uM
LJP5
3
K16
72
hr
1401 3613 4223 0.8555 0.7838
SK-BR-3 KIN001-043
0.37
uM
LJP6
1
C10
72
hr
1401 3313 4223 0.7845 0.6775
SK-BR-3 KIN001-043
0.37
uM
LJP6
2
C10
72
hr
1401 3295 4223 0.7802 0.6711
SK-BR-3 KIN001-043
0.37
uM
LJP6
3
C10
72
hr
1401 3325 4223 0.7873 0.6817
SK-BR-3 Alpelisib
0.37
uM
LJP5
1
N04
72
hr
1401 3145 4223 0.7447 0.6179
SK-BR-3 Alpelisib
0.37
uM
LJP5
2
N04
72
hr
1401 3544 4223 0.8392 0.7593
SK-BR-3 Alpelisib
0.37
uM
LJP5
3
N04
72
hr
1401 3337 4223 0.7902 0.6860
SK-BR-3 Luminespib
0.37
uM
LJP5
1
H16
72
hr
1401 1356 4223 0.3211 -0.0161
SK-BR-3 Luminespib
0.37
uM
LJP5
2
H16
72
hr
1401 1542 4223 0.3651 0.0498
SK-BR-3 Luminespib
0.37
uM
LJP5
3
H16
72
hr
1401 1855 4223 0.4393 0.1607