LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SK-BR-3 | BMS345541 | 0.37 | uM | LJP6 | 3 | D04 | 72 | hr | 1401 | 3936 | 4223 | 0.9320 | 0.8983 |
SK-BR-3 | SNS-032 | 0.37 | uM | LJP6 | 1 | H16 | 72 | hr | 1401 | 1085 | 4223 | 0.2569 | -0.1122 |
SK-BR-3 | SNS-032 | 0.37 | uM | LJP6 | 2 | H16 | 72 | hr | 1401 | 1139 | 4223 | 0.2697 | -0.0930 |
SK-BR-3 | SNS-032 | 0.37 | uM | LJP6 | 3 | H16 | 72 | hr | 1401 | 1141 | 4223 | 0.2702 | -0.0923 |
SK-BR-3 | GDC-0980 | 0.37 | uM | LJP5 | 1 | K22 | 72 | hr | 1401 | 1261 | 4223 | 0.2986 | -0.0498 |
SK-BR-3 | GDC-0980 | 0.37 | uM | LJP5 | 2 | K22 | 72 | hr | 1401 | 1342 | 4223 | 0.3178 | -0.0211 |
SK-BR-3 | GDC-0980 | 0.37 | uM | LJP5 | 3 | K22 | 72 | hr | 1401 | 1626 | 4223 | 0.3850 | 0.0796 |
SK-BR-3 | NVP-AEW541 | 0.37 | uM | LJP5 | 1 | E16 | 72 | hr | 1401 | 3551 | 4223 | 0.8409 | 0.7618 |
SK-BR-3 | NVP-AEW541 | 0.37 | uM | LJP5 | 2 | E16 | 72 | hr | 1401 | 3791 | 4223 | 0.8977 | 0.8469 |
SK-BR-3 | NVP-AEW541 | 0.37 | uM | LJP5 | 3 | E16 | 72 | hr | 1401 | 3992 | 4223 | 0.9453 | 0.9181 |
SK-BR-3 | SB590885 | 0.37 | uM | LJP5 | 1 | L16 | 72 | hr | 1401 | 4537 | 4223 | 1.0743 | 1.1113 |
SK-BR-3 | SB590885 | 0.37 | uM | LJP5 | 2 | L16 | 72 | hr | 1401 | 4587 | 4223 | 1.0862 | 1.1290 |
SK-BR-3 | SB590885 | 0.37 | uM | LJP5 | 3 | L16 | 72 | hr | 1401 | 4932 | 4223 | 1.1679 | 1.2512 |
SK-BR-3 | PIK-93 | 0.37 | uM | LJP5 | 1 | K16 | 72 | hr | 1401 | 3878 | 4223 | 0.9183 | 0.8777 |
SK-BR-3 | PIK-93 | 0.37 | uM | LJP5 | 2 | K16 | 72 | hr | 1401 | 4203 | 4223 | 0.9952 | 0.9929 |
SK-BR-3 | PIK-93 | 0.37 | uM | LJP5 | 3 | K16 | 72 | hr | 1401 | 3613 | 4223 | 0.8555 | 0.7838 |
SK-BR-3 | KIN001-043 | 0.37 | uM | LJP6 | 1 | C10 | 72 | hr | 1401 | 3313 | 4223 | 0.7845 | 0.6775 |
SK-BR-3 | KIN001-043 | 0.37 | uM | LJP6 | 2 | C10 | 72 | hr | 1401 | 3295 | 4223 | 0.7802 | 0.6711 |
SK-BR-3 | KIN001-043 | 0.37 | uM | LJP6 | 3 | C10 | 72 | hr | 1401 | 3325 | 4223 | 0.7873 | 0.6817 |
SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 1 | N04 | 72 | hr | 1401 | 3145 | 4223 | 0.7447 | 0.6179 |
SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 2 | N04 | 72 | hr | 1401 | 3544 | 4223 | 0.8392 | 0.7593 |
SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 3 | N04 | 72 | hr | 1401 | 3337 | 4223 | 0.7902 | 0.6860 |
SK-BR-3 | Luminespib | 0.37 | uM | LJP5 | 1 | H16 | 72 | hr | 1401 | 1356 | 4223 | 0.3211 | -0.0161 |
SK-BR-3 | Luminespib | 0.37 | uM | LJP5 | 2 | H16 | 72 | hr | 1401 | 1542 | 4223 | 0.3651 | 0.0498 |
SK-BR-3 | Luminespib | 0.37 | uM | LJP5 | 3 | H16 | 72 | hr | 1401 | 1855 | 4223 | 0.4393 | 0.1607 |