LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SK-BR-3 | Tozasertib | 0.37 | uM | LJP5 | 2 | B16 | 72 | hr | 1401 | 1508 | 4223 | 0.3571 | 0.0377 |
SK-BR-3 | Tozasertib | 0.37 | uM | LJP5 | 3 | B16 | 72 | hr | 1401 | 1475 | 4223 | 0.3493 | 0.0260 |
SK-BR-3 | Trametinib | 0.37 | uM | LJP5 | 1 | P22 | 72 | hr | 1401 | 3031 | 4223 | 0.7177 | 0.5775 |
SK-BR-3 | Trametinib | 0.37 | uM | LJP5 | 2 | P22 | 72 | hr | 1401 | 3446 | 4223 | 0.8160 | 0.7246 |
SK-BR-3 | Trametinib | 0.37 | uM | LJP5 | 3 | P22 | 72 | hr | 1401 | 3643 | 4223 | 0.8626 | 0.7944 |
SK-BR-3 | TWS119 | 0.37 | uM | LJP5 | 1 | M04 | 72 | hr | 1401 | 4197 | 4223 | 0.9938 | 0.9908 |
SK-BR-3 | TWS119 | 0.37 | uM | LJP5 | 2 | M04 | 72 | hr | 1401 | 4441 | 4223 | 1.0516 | 1.0772 |
SK-BR-3 | TWS119 | 0.37 | uM | LJP5 | 3 | M04 | 72 | hr | 1401 | 4708 | 4223 | 1.1148 | 1.1719 |
SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 1 | C16 | 72 | hr | 1401 | 4219 | 4223 | 0.9990 | 0.9986 |
SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 2 | C16 | 72 | hr | 1401 | 3768 | 4223 | 0.8922 | 0.8387 |
SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 3 | C16 | 72 | hr | 1401 | 4540 | 4223 | 1.0750 | 1.1123 |
SK-BR-3 | Withaferin A | 0.37 | uM | LJP5 | 1 | G16 | 72 | hr | 1401 | 1864 | 4223 | 0.4414 | 0.1639 |
SK-BR-3 | Withaferin A | 0.37 | uM | LJP5 | 2 | G16 | 72 | hr | 1401 | 2298 | 4223 | 0.5442 | 0.3177 |
SK-BR-3 | Withaferin A | 0.37 | uM | LJP5 | 3 | G16 | 72 | hr | 1401 | 2310 | 4223 | 0.5470 | 0.3220 |
SK-BR-3 | Withaferin A | 0.37 | uM | LJP6 | 1 | G16 | 72 | hr | 1401 | 2106 | 4223 | 0.4987 | 0.2497 |
SK-BR-3 | Withaferin A | 0.37 | uM | LJP6 | 2 | G16 | 72 | hr | 1401 | 1931 | 4223 | 0.4573 | 0.1877 |
SK-BR-3 | Withaferin A | 0.37 | uM | LJP6 | 3 | G16 | 72 | hr | 1401 | 1907 | 4223 | 0.4516 | 0.1792 |
SK-BR-3 | WYE-125132 | 0.37 | uM | LJP6 | 1 | L10 | 72 | hr | 1401 | 1754 | 4223 | 0.4153 | 0.1249 |
SK-BR-3 | WYE-125132 | 0.37 | uM | LJP6 | 2 | L10 | 72 | hr | 1401 | 1686 | 4223 | 0.3992 | 0.1008 |
SK-BR-3 | WYE-125132 | 0.37 | uM | LJP6 | 3 | L10 | 72 | hr | 1401 | 1783 | 4223 | 0.4222 | 0.1352 |
SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 1 | D22 | 72 | hr | 1401 | 1066 | 4223 | 0.2524 | -0.1189 |
SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 2 | D22 | 72 | hr | 1401 | 1025 | 4223 | 0.2427 | -0.1335 |
SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 3 | D22 | 72 | hr | 1401 | 980 | 4223 | 0.2321 | -0.1494 |
SK-BR-3 | XMD11-50 | 0.37 | uM | LJP6 | 1 | P10 | 72 | hr | 1401 | 3204 | 4223 | 0.7587 | 0.6388 |
SK-BR-3 | XMD11-50 | 0.37 | uM | LJP6 | 2 | P10 | 72 | hr | 1401 | 3461 | 4223 | 0.8195 | 0.7299 |