LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Tozasertib
0.37
uM
LJP5
2
B16
72
hr
1401 1508 4223 0.3571 0.0377
SK-BR-3 Tozasertib
0.37
uM
LJP5
3
B16
72
hr
1401 1475 4223 0.3493 0.0260
SK-BR-3 Trametinib
0.37
uM
LJP5
1
P22
72
hr
1401 3031 4223 0.7177 0.5775
SK-BR-3 Trametinib
0.37
uM
LJP5
2
P22
72
hr
1401 3446 4223 0.8160 0.7246
SK-BR-3 Trametinib
0.37
uM
LJP5
3
P22
72
hr
1401 3643 4223 0.8626 0.7944
SK-BR-3 TWS119
0.37
uM
LJP5
1
M04
72
hr
1401 4197 4223 0.9938 0.9908
SK-BR-3 TWS119
0.37
uM
LJP5
2
M04
72
hr
1401 4441 4223 1.0516 1.0772
SK-BR-3 TWS119
0.37
uM
LJP5
3
M04
72
hr
1401 4708 4223 1.1148 1.1719
SK-BR-3 Vemurafenib
0.37
uM
LJP5
1
C16
72
hr
1401 4219 4223 0.9990 0.9986
SK-BR-3 Vemurafenib
0.37
uM
LJP5
2
C16
72
hr
1401 3768 4223 0.8922 0.8387
SK-BR-3 Vemurafenib
0.37
uM
LJP5
3
C16
72
hr
1401 4540 4223 1.0750 1.1123
SK-BR-3 Withaferin A
0.37
uM
LJP5
1
G16
72
hr
1401 1864 4223 0.4414 0.1639
SK-BR-3 Withaferin A
0.37
uM
LJP5
2
G16
72
hr
1401 2298 4223 0.5442 0.3177
SK-BR-3 Withaferin A
0.37
uM
LJP5
3
G16
72
hr
1401 2310 4223 0.5470 0.3220
SK-BR-3 Withaferin A
0.37
uM
LJP6
1
G16
72
hr
1401 2106 4223 0.4987 0.2497
SK-BR-3 Withaferin A
0.37
uM
LJP6
2
G16
72
hr
1401 1931 4223 0.4573 0.1877
SK-BR-3 Withaferin A
0.37
uM
LJP6
3
G16
72
hr
1401 1907 4223 0.4516 0.1792
SK-BR-3 WYE-125132
0.37
uM
LJP6
1
L10
72
hr
1401 1754 4223 0.4153 0.1249
SK-BR-3 WYE-125132
0.37
uM
LJP6
2
L10
72
hr
1401 1686 4223 0.3992 0.1008
SK-BR-3 WYE-125132
0.37
uM
LJP6
3
L10
72
hr
1401 1783 4223 0.4222 0.1352
SK-BR-3 WZ3105
0.37
uM
LJP5
1
D22
72
hr
1401 1066 4223 0.2524 -0.1189
SK-BR-3 WZ3105
0.37
uM
LJP5
2
D22
72
hr
1401 1025 4223 0.2427 -0.1335
SK-BR-3 WZ3105
0.37
uM
LJP5
3
D22
72
hr
1401 980 4223 0.2321 -0.1494
SK-BR-3 XMD11-50
0.37
uM
LJP6
1
P10
72
hr
1401 3204 4223 0.7587 0.6388
SK-BR-3 XMD11-50
0.37
uM
LJP6
2
P10
72
hr
1401 3461 4223 0.8195 0.7299