LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 JW-7-24-1
0.12
uM
LJP6
1
B23
72
hr
1401 3459 4223 0.8191 0.7292
SK-BR-3 JW-7-24-1
0.12
uM
LJP6
2
B23
72
hr
1401 3390 4223 0.8027 0.7047
SK-BR-3 JW-7-24-1
0.12
uM
LJP6
3
B23
72
hr
1401 3219 4223 0.7622 0.6441
SK-BR-3 Lapatinib
0.12
uM
LJP6
1
M23
72
hr
1401 1401 4223 0.3318 -0.0002
SK-BR-3 Lapatinib
0.12
uM
LJP6
2
M23
72
hr
1401 1545 4223 0.3659 0.0508
SK-BR-3 Lapatinib
0.12
uM
LJP6
3
M23
72
hr
1401 1553 4223 0.3677 0.0537
SK-BR-3 LDN-193189
0.12
uM
LJP5
1
G05
72
hr
1401 3356 4223 0.7947 0.6927
SK-BR-3 LDN-193189
0.12
uM
LJP5
2
G05
72
hr
1401 4240 4223 1.0040 1.0060
SK-BR-3 LDN-193189
0.12
uM
LJP5
3
G05
72
hr
1401 4648 4223 1.1006 1.1506
SK-BR-3 Linifanib
0.12
uM
LJP6
1
J11
72
hr
1401 4527 4223 1.0720 1.1077
SK-BR-3 Linifanib
0.12
uM
LJP6
2
J11
72
hr
1401 4117 4223 0.9749 0.9624
SK-BR-3 Linifanib
0.12
uM
LJP6
3
J11
72
hr
1401 4795 4223 1.1354 1.2027
SK-BR-3 Linsitinib
0.12
uM
LJP5
1
O23
72
hr
1401 3418 4223 0.8094 0.7147
SK-BR-3 Linsitinib
0.12
uM
LJP5
2
O23
72
hr
1401 3944 4223 0.9339 0.9011
SK-BR-3 Linsitinib
0.12
uM
LJP5
3
O23
72
hr
1401 4254 4223 1.0073 1.0110
SK-BR-3 Mitoxantrone
0.12
uM
LJP5
1
C23
72
hr
1401 1582 4223 0.3746 0.0640
SK-BR-3 Mitoxantrone
0.12
uM
LJP5
2
C23
72
hr
1401 1558 4223 0.3689 0.0555
SK-BR-3 Mitoxantrone
0.12
uM
LJP5
3
C23
72
hr
1401 1404 4223 0.3325 0.0009
SK-BR-3 Mitoxantrone
0.12
uM
LJP6
1
C23
72
hr
1401 1510 4223 0.3576 0.0384
SK-BR-3 Mitoxantrone
0.12
uM
LJP6
2
C23
72
hr
1401 1439 4223 0.3408 0.0133
SK-BR-3 Mitoxantrone
0.12
uM
LJP6
3
C23
72
hr
1401 1355 4223 0.3209 -0.0165
SK-BR-3 MK2206
0.12
uM
LJP6
1
F05
72
hr
1401 2771 4223 0.6562 0.4854
SK-BR-3 MK2206
0.12
uM
LJP6
2
F05
72
hr
1401 2767 4223 0.6552 0.4839
SK-BR-3 MK2206
0.12
uM
LJP6
3
F05
72
hr
1401 2923 4223 0.6922 0.5392
SK-BR-3 Neratinib
0.12
uM
LJP5
1
A17
72
hr
1401 1416 4223 0.3353 0.0051