LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SK-BR-3 | Neratinib | 0.12 | uM | LJP5 | 2 | A17 | 72 | hr | 1401 | 1574 | 4223 | 0.3727 | 0.0611 |
SK-BR-3 | Neratinib | 0.12 | uM | LJP5 | 3 | A17 | 72 | hr | 1401 | 1544 | 4223 | 0.3656 | 0.0505 |
SK-BR-3 | Nilotinib | 0.12 | uM | LJP5 | 1 | N17 | 72 | hr | 1401 | 4192 | 4223 | 0.9926 | 0.9890 |
SK-BR-3 | Nilotinib | 0.12 | uM | LJP5 | 2 | N17 | 72 | hr | 1401 | 4714 | 4223 | 1.1162 | 1.1740 |
SK-BR-3 | Nilotinib | 0.12 | uM | LJP5 | 3 | N17 | 72 | hr | 1401 | 5276 | 4223 | 1.2493 | 1.3732 |
SK-BR-3 | Nintedanib | 0.12 | uM | LJP6 | 1 | H05 | 72 | hr | 1401 | 4092 | 4223 | 0.9690 | 0.9535 |
SK-BR-3 | Nintedanib | 0.12 | uM | LJP6 | 2 | H05 | 72 | hr | 1401 | 3933 | 4223 | 0.9313 | 0.8972 |
SK-BR-3 | Nintedanib | 0.12 | uM | LJP6 | 3 | H05 | 72 | hr | 1401 | 4139 | 4223 | 0.9801 | 0.9702 |
SK-BR-3 | NU7441 | 0.12 | uM | LJP5 | 1 | C11 | 72 | hr | 1401 | 4293 | 4223 | 1.0166 | 1.0248 |
SK-BR-3 | NU7441 | 0.12 | uM | LJP5 | 2 | C11 | 72 | hr | 1401 | 3907 | 4223 | 0.9252 | 0.8880 |
SK-BR-3 | NU7441 | 0.12 | uM | LJP5 | 3 | C11 | 72 | hr | 1401 | 3721 | 4223 | 0.8811 | 0.8221 |
SK-BR-3 | Dactolisib | 0.12 | uM | LJP5 | 1 | M17 | 72 | hr | 1401 | 1402 | 4223 | 0.3320 | 0.0002 |
SK-BR-3 | Dactolisib | 0.12 | uM | LJP5 | 2 | M17 | 72 | hr | 1401 | 1618 | 4223 | 0.3831 | 0.0767 |
SK-BR-3 | Dactolisib | 0.12 | uM | LJP5 | 3 | M17 | 72 | hr | 1401 | 1659 | 4223 | 0.3928 | 0.0913 |
SK-BR-3 | NVP-TAE684 | 0.12 | uM | LJP6 | 1 | K17 | 72 | hr | 1401 | 4035 | 4223 | 0.9555 | 0.9333 |
SK-BR-3 | NVP-TAE684 | 0.12 | uM | LJP6 | 2 | K17 | 72 | hr | 1401 | 4270 | 4223 | 1.0111 | 1.0166 |
SK-BR-3 | NVP-TAE684 | 0.12 | uM | LJP6 | 3 | K17 | 72 | hr | 1401 | 4299 | 4223 | 1.0180 | 1.0269 |
SK-BR-3 | Palbociclib | 0.12 | uM | LJP6 | 1 | E17 | 72 | hr | 1401 | 3117 | 4223 | 0.7381 | 0.6080 |
SK-BR-3 | Palbociclib | 0.12 | uM | LJP6 | 2 | E17 | 72 | hr | 1401 | 2966 | 4223 | 0.7023 | 0.5545 |
SK-BR-3 | Palbociclib | 0.12 | uM | LJP6 | 3 | E17 | 72 | hr | 1401 | 3161 | 4223 | 0.7485 | 0.6236 |
SK-BR-3 | PD0325901 | 0.12 | uM | LJP5 | 1 | C05 | 72 | hr | 1401 | 3699 | 4223 | 0.8759 | 0.8143 |
SK-BR-3 | PD0325901 | 0.12 | uM | LJP5 | 2 | C05 | 72 | hr | 1401 | 3840 | 4223 | 0.9093 | 0.8642 |
SK-BR-3 | PD0325901 | 0.12 | uM | LJP5 | 3 | C05 | 72 | hr | 1401 | 4257 | 4223 | 1.0080 | 1.0120 |
SK-BR-3 | PD0325901 | 0.12 | uM | LJP6 | 1 | E05 | 72 | hr | 1401 | 3562 | 4223 | 0.8435 | 0.7657 |
SK-BR-3 | PD0325901 | 0.12 | uM | LJP6 | 2 | E05 | 72 | hr | 1401 | 3992 | 4223 | 0.9453 | 0.9181 |