LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Neratinib
0.12
uM
LJP5
2
A17
72
hr
1401 1574 4223 0.3727 0.0611
SK-BR-3 Neratinib
0.12
uM
LJP5
3
A17
72
hr
1401 1544 4223 0.3656 0.0505
SK-BR-3 Nilotinib
0.12
uM
LJP5
1
N17
72
hr
1401 4192 4223 0.9926 0.9890
SK-BR-3 Nilotinib
0.12
uM
LJP5
2
N17
72
hr
1401 4714 4223 1.1162 1.1740
SK-BR-3 Nilotinib
0.12
uM
LJP5
3
N17
72
hr
1401 5276 4223 1.2493 1.3732
SK-BR-3 Nintedanib
0.12
uM
LJP6
1
H05
72
hr
1401 4092 4223 0.9690 0.9535
SK-BR-3 Nintedanib
0.12
uM
LJP6
2
H05
72
hr
1401 3933 4223 0.9313 0.8972
SK-BR-3 Nintedanib
0.12
uM
LJP6
3
H05
72
hr
1401 4139 4223 0.9801 0.9702
SK-BR-3 NU7441
0.12
uM
LJP5
1
C11
72
hr
1401 4293 4223 1.0166 1.0248
SK-BR-3 NU7441
0.12
uM
LJP5
2
C11
72
hr
1401 3907 4223 0.9252 0.8880
SK-BR-3 NU7441
0.12
uM
LJP5
3
C11
72
hr
1401 3721 4223 0.8811 0.8221
SK-BR-3 Dactolisib
0.12
uM
LJP5
1
M17
72
hr
1401 1402 4223 0.3320 0.0002
SK-BR-3 Dactolisib
0.12
uM
LJP5
2
M17
72
hr
1401 1618 4223 0.3831 0.0767
SK-BR-3 Dactolisib
0.12
uM
LJP5
3
M17
72
hr
1401 1659 4223 0.3928 0.0913
SK-BR-3 NVP-TAE684
0.12
uM
LJP6
1
K17
72
hr
1401 4035 4223 0.9555 0.9333
SK-BR-3 NVP-TAE684
0.12
uM
LJP6
2
K17
72
hr
1401 4270 4223 1.0111 1.0166
SK-BR-3 NVP-TAE684
0.12
uM
LJP6
3
K17
72
hr
1401 4299 4223 1.0180 1.0269
SK-BR-3 Palbociclib
0.12
uM
LJP6
1
E17
72
hr
1401 3117 4223 0.7381 0.6080
SK-BR-3 Palbociclib
0.12
uM
LJP6
2
E17
72
hr
1401 2966 4223 0.7023 0.5545
SK-BR-3 Palbociclib
0.12
uM
LJP6
3
E17
72
hr
1401 3161 4223 0.7485 0.6236
SK-BR-3 PD0325901
0.12
uM
LJP5
1
C05
72
hr
1401 3699 4223 0.8759 0.8143
SK-BR-3 PD0325901
0.12
uM
LJP5
2
C05
72
hr
1401 3840 4223 0.9093 0.8642
SK-BR-3 PD0325901
0.12
uM
LJP5
3
C05
72
hr
1401 4257 4223 1.0080 1.0120
SK-BR-3 PD0325901
0.12
uM
LJP6
1
E05
72
hr
1401 3562 4223 0.8435 0.7657
SK-BR-3 PD0325901
0.12
uM
LJP6
2
E05
72
hr
1401 3992 4223 0.9453 0.9181