LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SK-BR-3 | TGX221 | 0.04 | uM | LJP5 | 1 | H24 | 72 | hr | 1401 | 3455 | 4223 | 0.8181 | 0.7278 |
SK-BR-3 | TGX221 | 0.04 | uM | LJP5 | 2 | H24 | 72 | hr | 1401 | 3153 | 4223 | 0.7466 | 0.6208 |
SK-BR-3 | TGX221 | 0.04 | uM | LJP5 | 3 | H24 | 72 | hr | 1401 | 3783 | 4223 | 0.8958 | 0.8440 |
SK-BR-3 | Torin1 | 0.04 | uM | LJP6 | 1 | O18 | 72 | hr | 1401 | 1818 | 4223 | 0.4305 | 0.1476 |
SK-BR-3 | Torin1 | 0.04 | uM | LJP6 | 2 | O18 | 72 | hr | 1401 | 1940 | 4223 | 0.4594 | 0.1908 |
SK-BR-3 | Torin1 | 0.04 | uM | LJP6 | 3 | O18 | 72 | hr | 1401 | 1925 | 4223 | 0.4558 | 0.1855 |
SK-BR-3 | Torin2 | 0.04 | uM | LJP5 | 1 | I24 | 72 | hr | 1401 | 1085 | 4223 | 0.2569 | -0.1122 |
SK-BR-3 | Torin2 | 0.04 | uM | LJP5 | 2 | I24 | 72 | hr | 1401 | 1377 | 4223 | 0.3261 | -0.0087 |
SK-BR-3 | Torin2 | 0.04 | uM | LJP5 | 3 | I24 | 72 | hr | 1401 | 1387 | 4223 | 0.3284 | -0.0051 |
SK-BR-3 | Tozasertib | 0.04 | uM | LJP5 | 1 | B18 | 72 | hr | 1401 | 1320 | 4223 | 0.3126 | -0.0289 |
SK-BR-3 | Tozasertib | 0.04 | uM | LJP5 | 2 | B18 | 72 | hr | 1401 | 1266 | 4223 | 0.2998 | -0.0480 |
SK-BR-3 | Tozasertib | 0.04 | uM | LJP5 | 3 | B18 | 72 | hr | 1401 | 1426 | 4223 | 0.3377 | 0.0087 |
SK-BR-3 | Trametinib | 0.04 | uM | LJP5 | 1 | P24 | 72 | hr | 1401 | 2838 | 4223 | 0.6720 | 0.5091 |
SK-BR-3 | Trametinib | 0.04 | uM | LJP5 | 2 | P24 | 72 | hr | 1401 | 3328 | 4223 | 0.7881 | 0.6828 |
SK-BR-3 | Trametinib | 0.04 | uM | LJP5 | 3 | P24 | 72 | hr | 1401 | 3678 | 4223 | 0.8709 | 0.8068 |
SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 1 | M06 | 72 | hr | 1401 | 5060 | 4223 | 1.1982 | 1.2966 |
SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 2 | M06 | 72 | hr | 1401 | 4740 | 4223 | 1.1224 | 1.1832 |
SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 3 | M06 | 72 | hr | 1401 | 4689 | 4223 | 1.1103 | 1.1651 |
SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 1 | C18 | 72 | hr | 1401 | 4308 | 4223 | 1.0201 | 1.0301 |
SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 2 | C18 | 72 | hr | 1401 | 4659 | 4223 | 1.1032 | 1.1545 |
SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 3 | C18 | 72 | hr | 1401 | 4694 | 4223 | 1.1115 | 1.1669 |
SK-BR-3 | Withaferin A | 0.04 | uM | LJP5 | 1 | G18 | 72 | hr | 1401 | 3924 | 4223 | 0.9292 | 0.8940 |
SK-BR-3 | Withaferin A | 0.04 | uM | LJP5 | 2 | G18 | 72 | hr | 1401 | 4109 | 4223 | 0.9730 | 0.9596 |
SK-BR-3 | Withaferin A | 0.04 | uM | LJP5 | 3 | G18 | 72 | hr | 1401 | 4479 | 4223 | 1.0606 | 1.0907 |
SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 1 | G18 | 72 | hr | 1401 | 4258 | 4223 | 1.0083 | 1.0124 |