LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 TGX221
0.04
uM
LJP5
1
H24
72
hr
1401 3455 4223 0.8181 0.7278
SK-BR-3 TGX221
0.04
uM
LJP5
2
H24
72
hr
1401 3153 4223 0.7466 0.6208
SK-BR-3 TGX221
0.04
uM
LJP5
3
H24
72
hr
1401 3783 4223 0.8958 0.8440
SK-BR-3 Torin1
0.04
uM
LJP6
1
O18
72
hr
1401 1818 4223 0.4305 0.1476
SK-BR-3 Torin1
0.04
uM
LJP6
2
O18
72
hr
1401 1940 4223 0.4594 0.1908
SK-BR-3 Torin1
0.04
uM
LJP6
3
O18
72
hr
1401 1925 4223 0.4558 0.1855
SK-BR-3 Torin2
0.04
uM
LJP5
1
I24
72
hr
1401 1085 4223 0.2569 -0.1122
SK-BR-3 Torin2
0.04
uM
LJP5
2
I24
72
hr
1401 1377 4223 0.3261 -0.0087
SK-BR-3 Torin2
0.04
uM
LJP5
3
I24
72
hr
1401 1387 4223 0.3284 -0.0051
SK-BR-3 Tozasertib
0.04
uM
LJP5
1
B18
72
hr
1401 1320 4223 0.3126 -0.0289
SK-BR-3 Tozasertib
0.04
uM
LJP5
2
B18
72
hr
1401 1266 4223 0.2998 -0.0480
SK-BR-3 Tozasertib
0.04
uM
LJP5
3
B18
72
hr
1401 1426 4223 0.3377 0.0087
SK-BR-3 Trametinib
0.04
uM
LJP5
1
P24
72
hr
1401 2838 4223 0.6720 0.5091
SK-BR-3 Trametinib
0.04
uM
LJP5
2
P24
72
hr
1401 3328 4223 0.7881 0.6828
SK-BR-3 Trametinib
0.04
uM
LJP5
3
P24
72
hr
1401 3678 4223 0.8709 0.8068
SK-BR-3 TWS119
0.04
uM
LJP5
1
M06
72
hr
1401 5060 4223 1.1982 1.2966
SK-BR-3 TWS119
0.04
uM
LJP5
2
M06
72
hr
1401 4740 4223 1.1224 1.1832
SK-BR-3 TWS119
0.04
uM
LJP5
3
M06
72
hr
1401 4689 4223 1.1103 1.1651
SK-BR-3 Vemurafenib
0.04
uM
LJP5
1
C18
72
hr
1401 4308 4223 1.0201 1.0301
SK-BR-3 Vemurafenib
0.04
uM
LJP5
2
C18
72
hr
1401 4659 4223 1.1032 1.1545
SK-BR-3 Vemurafenib
0.04
uM
LJP5
3
C18
72
hr
1401 4694 4223 1.1115 1.1669
SK-BR-3 Withaferin A
0.04
uM
LJP5
1
G18
72
hr
1401 3924 4223 0.9292 0.8940
SK-BR-3 Withaferin A
0.04
uM
LJP5
2
G18
72
hr
1401 4109 4223 0.9730 0.9596
SK-BR-3 Withaferin A
0.04
uM
LJP5
3
G18
72
hr
1401 4479 4223 1.0606 1.0907
SK-BR-3 Withaferin A
0.04
uM
LJP6
1
G18
72
hr
1401 4258 4223 1.0083 1.0124