LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 2 | G18 | 72 | hr | 1401 | 4611 | 4223 | 1.0919 | 1.1375 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 3 | G18 | 72 | hr | 1401 | 4550 | 4223 | 1.0774 | 1.1159 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 1 | L12 | 72 | hr | 1401 | 1539 | 4223 | 0.3644 | 0.0487 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 2 | L12 | 72 | hr | 1401 | 1660 | 4223 | 0.3931 | 0.0916 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 3 | L12 | 72 | hr | 1401 | 1790 | 4223 | 0.4239 | 0.1377 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 1 | D24 | 72 | hr | 1401 | 894 | 4223 | 0.2117 | -0.1799 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 2 | D24 | 72 | hr | 1401 | 822 | 4223 | 0.1946 | -0.2054 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 3 | D24 | 72 | hr | 1401 | 1000 | 4223 | 0.2368 | -0.1423 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 1 | P12 | 72 | hr | 1401 | 3805 | 4223 | 0.9010 | 0.8518 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 2 | P12 | 72 | hr | 1401 | 3768 | 4223 | 0.8922 | 0.8387 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 3 | P12 | 72 | hr | 1401 | 3677 | 4223 | 0.8707 | 0.8065 |
| SK-BR-3 | Y39983 | 0.04 | uM | LJP6 | 1 | P06 | 72 | hr | 1401 | 4424 | 4223 | 1.0476 | 1.0712 |
| SK-BR-3 | Y39983 | 0.04 | uM | LJP6 | 2 | P06 | 72 | hr | 1401 | 3891 | 4223 | 0.9214 | 0.8823 |
| SK-BR-3 | Y39983 | 0.04 | uM | LJP6 | 3 | P06 | 72 | hr | 1401 | 4417 | 4223 | 1.0459 | 1.0687 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 1 | N12 | 72 | hr | 1401 | 4648 | 4223 | 1.1006 | 1.1506 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 2 | N12 | 72 | hr | 1401 | 4887 | 4223 | 1.1572 | 1.2353 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 3 | N12 | 72 | hr | 1401 | 4908 | 4223 | 1.1622 | 1.2427 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 1 | M18 | 72 | hr | 1401 | 2951 | 4223 | 0.6988 | 0.5492 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 2 | M18 | 72 | hr | 1401 | 3276 | 4223 | 0.7757 | 0.6643 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 3 | M18 | 72 | hr | 1401 | 3560 | 4223 | 0.8430 | 0.7650 |
| SK-BR-3 | Afatinib | 0.12 | uM | LJP6 | 1 | G23 | 72 | hr | 1401 | 1536 | 4223 | 0.3637 | 0.0477 |
| SK-BR-3 | Afatinib | 0.12 | uM | LJP6 | 2 | G23 | 72 | hr | 1401 | 1378 | 4223 | 0.3263 | -0.0083 |
| SK-BR-3 | Afatinib | 0.12 | uM | LJP6 | 3 | G23 | 72 | hr | 1401 | 1335 | 4223 | 0.3161 | -0.0236 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 1 | B23 | 72 | hr | 1401 | 3430 | 4223 | 0.8122 | 0.7189 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 2 | B23 | 72 | hr | 1401 | 3587 | 4223 | 0.8494 | 0.7746 |