LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 SU11274
10.0
uM
LJP5
 2
J07
 72
hr
 1235 1118 4513 0.2477 -0.0360
MDA-MB-231 SU11274
10.0
uM
LJP5
 3
J07
 72
hr
 1235 1255 4513 0.2781 0.0058
MDA-MB-231 Fedratinib
10.0
uM
LJP5
 1
L01
 72
hr
 1235 379 4513 0.0840 -0.2615
MDA-MB-231 Fedratinib
10.0
uM
LJP5
 2
L01
 72
hr
 1235 297 4513 0.0658 -0.2865
MDA-MB-231 Fedratinib
10.0
uM
LJP5
 3
L01
 72
hr
 1235 518 4513 0.1148 -0.2190
MDA-MB-231 TGX221
10.0
uM
LJP5
 1
H19
 72
hr
 1235 3855 4513 0.8541 0.7991
MDA-MB-231 TGX221
10.0
uM
LJP5
 2
H19
 72
hr
 1235 3974 4513 0.8804 0.8354
MDA-MB-231 TGX221
10.0
uM
LJP5
 3
H19
 72
hr
 1235 4403 4513 0.9755 0.9662
MDA-MB-231 Torin1
10.0
uM
LJP6
 1
O13
 72
hr
 1235 905 4513 0.2005 -0.1010
MDA-MB-231 Torin1
10.0
uM
LJP6
 2
O13
 72
hr
 1235 1041 4513 0.2306 -0.0595
MDA-MB-231 Torin1
10.0
uM
LJP6
 3
O13
 72
hr
 1235 1016 4513 0.2251 -0.0671
MDA-MB-231 Torin2
10.0
uM
LJP5
 1
I19
 72
hr
 1235 455 4513 0.1008 -0.2383
MDA-MB-231 Torin2
10.0
uM
LJP5
 2
I19
 72
hr
 1235 499 4513 0.1106 -0.2248
MDA-MB-231 Torin2
10.0
uM
LJP5
 3
I19
 72
hr
 1235 649 4513 0.1438 -0.1791
MDA-MB-231 Tozasertib
10.0
uM
LJP5
 1
B13
 72
hr
 1235 1259 4513 0.2789 0.0070
MDA-MB-231 Tozasertib
10.0
uM
LJP5
 2
B13
 72
hr
 1235 1173 4513 0.2599 -0.0192
MDA-MB-231 Tozasertib
10.0
uM
LJP5
 3
B13
 72
hr
 1235 1353 4513 0.2998 0.0357
MDA-MB-231 Trametinib
10.0
uM
LJP5
 1
P19
 72
hr
 1235 1148 4513 0.2543 -0.0268
MDA-MB-231 Trametinib
10.0
uM
LJP5
 2
P19
 72
hr
 1235 1240 4513 0.2747 0.0012
MDA-MB-231 Trametinib
10.0
uM
LJP5
 3
P19
 72
hr
 1235 1469 4513 0.3255 0.0711
MDA-MB-231 TWS119
10.0
uM
LJP5
 1
M01
 72
hr
 1235 1293 4513 0.2865 0.0174
MDA-MB-231 TWS119
10.0
uM
LJP5
 2
M01
 72
hr
 1235 1321 4513 0.2927 0.0259
MDA-MB-231 TWS119
10.0
uM
LJP5
 3
M01
 72
hr
 1235 1285 4513 0.2847 0.0150
MDA-MB-231 Vemurafenib
10.0
uM
LJP5
 1
C13
 72
hr
 1235 2106 4513 0.4666 0.2655
MDA-MB-231 Vemurafenib
10.0
uM
LJP5
 2
C13
 72
hr
 1235 2395 4513 0.5306 0.3536