LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Radicicol
10.0
uM
LJP6
 1
K07
 72
hr
 1235 769 4513 0.1704 -0.1425
MDA-MB-231 Radicicol
10.0
uM
LJP6
 2
K07
 72
hr
 1235 771 4513 0.1708 -0.1419
MDA-MB-231 Radicicol
10.0
uM
LJP6
 3
K07
 72
hr
 1235 959 4513 0.2125 -0.0845
MDA-MB-231 Seliciclib
10.0
uM
LJP5
 1
J01
 72
hr
 1235 2296 4513 0.5087 0.3234
MDA-MB-231 Seliciclib
10.0
uM
LJP5
 2
J01
 72
hr
 1235 2364 4513 0.5238 0.3442
MDA-MB-231 Seliciclib
10.0
uM
LJP5
 3
J01
 72
hr
 1235 2730 4513 0.6048 0.4558
MDA-MB-231 Ruxolitinib
10.0
uM
LJP5
 1
O13
 72
hr
 1235 2255 4513 0.4996 0.3109
MDA-MB-231 Ruxolitinib
10.0
uM
LJP5
 2
O13
 72
hr
 1235 2029 4513 0.4495 0.2420
MDA-MB-231 Ruxolitinib
10.0
uM
LJP5
 3
O13
 72
hr
 1235 2517 4513 0.5576 0.3908
MDA-MB-231 XL147
10.0
uM
LJP5
 1
G07
 72
hr
 1235 3986 4513 0.8831 0.8390
MDA-MB-231 XL147
10.0
uM
LJP5
 2
G07
 72
hr
 1235 4327 4513 0.9587 0.9431
MDA-MB-231 XL147
10.0
uM
LJP5
 3
G07
 72
hr
 1235 4192 4513 0.9287 0.9019
MDA-MB-231 Saracatinib
10.0
uM
LJP6
 1
D07
 72
hr
 1235 1927 4513 0.4269 0.2108
MDA-MB-231 Saracatinib
10.0
uM
LJP6
 2
D07
 72
hr
 1235 1921 4513 0.4256 0.2090
MDA-MB-231 Saracatinib
10.0
uM
LJP6
 3
D07
 72
hr
 1235 2402 4513 0.5322 0.3558
MDA-MB-231 Selumetinib
10.0
uM
LJP6
 1
M07
 72
hr
 1235 1652 4513 0.3660 0.1269
MDA-MB-231 Selumetinib
10.0
uM
LJP6
 2
M07
 72
hr
 1235 1483 4513 0.3286 0.0754
MDA-MB-231 Selumetinib
10.0
uM
LJP6
 3
M07
 72
hr
 1235 1597 4513 0.3538 0.1102
MDA-MB-231 Sirolimus
10.0
uM
LJP6
 1
L13
 72
hr
 1235 3357 4513 0.7438 0.6471
MDA-MB-231 Sirolimus
10.0
uM
LJP6
 2
L13
 72
hr
 1235 3042 4513 0.6740 0.5510
MDA-MB-231 Sirolimus
10.0
uM
LJP6
 3
L13
 72
hr
 1235 3424 4513 0.7586 0.6676
MDA-MB-231 Sorafenib
10.0
uM
LJP6
 1
B07
 72
hr
 1235 3699 4513 0.8195 0.7515
MDA-MB-231 Sorafenib
10.0
uM
LJP6
 2
B07
 72
hr
 1235 3551 4513 0.7867 0.7063
MDA-MB-231 Sorafenib
10.0
uM
LJP6
 3
B07
 72
hr
 1235 4209 4513 0.9325 0.9071
MDA-MB-231 SU11274
10.0
uM
LJP5
 1
J07
 72
hr
 1235 1095 4513 0.2426 -0.0430