LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Geldanamycin
10.0
uM
LJP5
 2
O01
 72
hr
 1235 454 4513 0.1006 -0.2386
MDA-MB-231 Geldanamycin
10.0
uM
LJP5
 3
O01
 72
hr
 1235 585 4513 0.1296 -0.1986
MDA-MB-231 Geldanamycin
10.0
uM
LJP6
 1
O01
 72
hr
 1235 347 4513 0.0769 -0.2712
MDA-MB-231 Geldanamycin
10.0
uM
LJP6
 2
O01
 72
hr
 1235 149 4513 0.0330 -0.3316
MDA-MB-231 Geldanamycin
10.0
uM
LJP6
 3
O01
 72
hr
 1235 507 4513 0.1123 -0.2224
MDA-MB-231 GSK1059615
10.0
uM
LJP5
 1
E01
 72
hr
 1235 503 4513 0.1114 -0.2236
MDA-MB-231 GSK1059615
10.0
uM
LJP5
 2
E01
 72
hr
 1235 381 4513 0.0844 -0.2608
MDA-MB-231 GSK1059615
10.0
uM
LJP5
 3
E01
 72
hr
 1235 670 4513 0.1484 -0.1727
MDA-MB-231 GSK1059615
10.0
uM
LJP6
 1
C01
 72
hr
 1235 837 4513 0.1854 -0.1217
MDA-MB-231 GSK1059615
10.0
uM
LJP6
 2
C01
 72
hr
 1235 437 4513 0.0968 -0.2438
MDA-MB-231 GSK1059615
10.0
uM
LJP6
 3
C01
 72
hr
 1235 1265 4513 0.2803 0.0089
MDA-MB-231 GSK1904529A
10.0
uM
LJP6
 1
H19
 72
hr
 1235 4212 4513 0.9332 0.9080
MDA-MB-231 GSK1904529A
10.0
uM
LJP6
 2
H19
 72
hr
 1235 4261 4513 0.9440 0.9229
MDA-MB-231 GSK1904529A
10.0
uM
LJP6
 3
H19
 72
hr
 1235 4188 4513 0.9279 0.9007
MDA-MB-231 Omipalisib
10.0
uM
LJP6
 1
N01
 72
hr
 1235 701 4513 0.1553 -0.1632
MDA-MB-231 Omipalisib
10.0
uM
LJP6
 2
N01
 72
hr
 1235 687 4513 0.1522 -0.1675
MDA-MB-231 Omipalisib
10.0
uM
LJP6
 3
N01
 72
hr
 1235 781 4513 0.1730 -0.1388
MDA-MB-231 GSK 690693
10.0
uM
LJP5
 1
F19
 72
hr
 1235 3477 4513 0.7703 0.6837
MDA-MB-231 GSK 690693
10.0
uM
LJP5
 2
F19
 72
hr
 1235 3788 4513 0.8392 0.7786
MDA-MB-231 GSK 690693
10.0
uM
LJP5
 3
F19
 72
hr
 1235 3890 4513 0.8618 0.8097
MDA-MB-231 GW843682X
10.0
uM
LJP6
 1
B13
 72
hr
 1235 1083 4513 0.2399 -0.0467
MDA-MB-231 GW843682X
10.0
uM
LJP6
 2
B13
 72
hr
 1235 1013 4513 0.2244 -0.0680
MDA-MB-231 GW843682X
10.0
uM
LJP6
 3
B13
 72
hr
 1235 1391 4513 0.3082 0.0473
MDA-MB-231 HG-5-113-01
10.0
uM
LJP5
 1
B07
 72
hr
 1235 810 4513 0.1795 -0.1300
MDA-MB-231 HG-5-113-01
10.0
uM
LJP5
 2
B07
 72
hr
 1235 699 4513 0.1549 -0.1638