LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Dasatinib
10.0
uM
LJP6
 1
I01
 72
hr
 1235 468 4513 0.1037 -0.2343
MDA-MB-231 Dasatinib
10.0
uM
LJP6
 2
I01
 72
hr
 1235 229 4513 0.0507 -0.3072
MDA-MB-231 Dasatinib
10.0
uM
LJP6
 3
I01
 72
hr
 1235 613 4513 0.1358 -0.1901
MDA-MB-231 Dovitinib
10.0
uM
LJP5
 1
E19
 72
hr
 1235 1480 4513 0.3279 0.0745
MDA-MB-231 Dovitinib
10.0
uM
LJP5
 2
E19
 72
hr
 1235 1479 4513 0.3277 0.0742
MDA-MB-231 Dovitinib
10.0
uM
LJP5
 3
E19
 72
hr
 1235 1686 4513 0.3735 0.1373
MDA-MB-231 Enzastaurin
10.0
uM
LJP5
 1
D13
 72
hr
 1235 4842 4513 1.0727 1.1002
MDA-MB-231 Enzastaurin
10.0
uM
LJP5
 2
D13
 72
hr
 1235 5273 4513 1.1682 1.2317
MDA-MB-231 Enzastaurin
10.0
uM
LJP5
 3
D13
 72
hr
 1235 5417 4513 1.2001 1.2756
MDA-MB-231 Erlotinib
10.0
uM
LJP5
 1
M19
 72
hr
 1235 2846 4513 0.6305 0.4912
MDA-MB-231 Erlotinib
10.0
uM
LJP5
 2
M19
 72
hr
 1235 3305 4513 0.7322 0.6313
MDA-MB-231 Erlotinib
10.0
uM
LJP5
 3
M19
 72
hr
 1235 3611 4513 0.8000 0.7246
MDA-MB-231 Foretinib
10.0
uM
LJP5
 1
H07
 72
hr
 1235 633 4513 0.1402 -0.1840
MDA-MB-231 Foretinib
10.0
uM
LJP5
 2
H07
 72
hr
 1235 712 4513 0.1577 -0.1599
MDA-MB-231 Foretinib
10.0
uM
LJP5
 3
H07
 72
hr
 1235 780 4513 0.1728 -0.1391
MDA-MB-231 R406
10.0
uM
LJP6
 1
C13
 72
hr
 1235 1228 4513 0.2721 -0.0024
MDA-MB-231 R406
10.0
uM
LJP6
 2
C13
 72
hr
 1235 1475 4513 0.3268 0.0729
MDA-MB-231 R406
10.0
uM
LJP6
 3
C13
 72
hr
 1235 1242 4513 0.2752 0.0018
MDA-MB-231 Pictilisib
10.0
uM
LJP6
 1
D19
 72
hr
 1235 1759 4513 0.3897 0.1596
MDA-MB-231 Pictilisib
10.0
uM
LJP6
 2
D19
 72
hr
 1235 1922 4513 0.4258 0.2093
MDA-MB-231 Pictilisib
10.0
uM
LJP6
 3
D19
 72
hr
 1235 1926 4513 0.4267 0.2105
MDA-MB-231 Gefitinib
10.0
uM
LJP6
 1
N07
 72
hr
 1235 3943 4513 0.8736 0.8259
MDA-MB-231 Gefitinib
10.0
uM
LJP6
 2
N07
 72
hr
 1235 3861 4513 0.8554 0.8009
MDA-MB-231 Gefitinib
10.0
uM
LJP6
 3
N07
 72
hr
 1235 4041 4513 0.8953 0.8558
MDA-MB-231 Geldanamycin
10.0
uM
LJP5
 1
O01
 72
hr
 1235 586 4513 0.1298 -0.1983