LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Selumetinib
0.37
uM
LJP6
1
M10
72
hr
1097 3682 3769 0.9768 0.9672
BT-20 Selumetinib
0.37
uM
LJP6
2
M10
72
hr
1097 3431 3769 0.9102 0.8733
BT-20 Selumetinib
0.37
uM
LJP6
3
M10
72
hr
1097 3500 3769 0.9285 0.8991
BT-20 Sirolimus
0.37
uM
LJP6
1
L16
72
hr
1097 2251 3769 0.5972 0.4317
BT-20 Sirolimus
0.37
uM
LJP6
2
L16
72
hr
1097 2099 3769 0.5568 0.3749
BT-20 Sirolimus
0.37
uM
LJP6
3
L16
72
hr
1097 2209 3769 0.5860 0.4160
BT-20 Sorafenib
0.37
uM
LJP6
1
B10
72
hr
1097 3202 3769 0.8494 0.7876
BT-20 Sorafenib
0.37
uM
LJP6
2
B10
72
hr
1097 3286 3769 0.8717 0.8191
BT-20 Sorafenib
0.37
uM
LJP6
3
B10
72
hr
1097 2662 3769 0.7062 0.5856
BT-20 SU11274
0.37
uM
LJP5
1
J10
72
hr
1097 3940 3769 1.0452 1.0638
BT-20 SU11274
0.37
uM
LJP5
2
J10
72
hr
1097 3881 3769 1.0296 1.0417
BT-20 SU11274
0.37
uM
LJP5
3
J10
72
hr
1097 3919 3769 1.0396 1.0559
BT-20 Fedratinib
0.37
uM
LJP5
1
L04
72
hr
1097 3574 3769 0.9481 0.9268
BT-20 Fedratinib
0.37
uM
LJP5
2
L04
72
hr
1097 3642 3769 0.9662 0.9523
BT-20 Fedratinib
0.37
uM
LJP5
3
L04
72
hr
1097 3401 3769 0.9022 0.8621
BT-20 TGX221
0.37
uM
LJP5
1
H22
72
hr
1097 3712 3769 0.9847 0.9785
BT-20 TGX221
0.37
uM
LJP5
2
H22
72
hr
1097 3770 3769 1.0001 1.0002
BT-20 TGX221
0.37
uM
LJP5
3
H22
72
hr
1097 3988 3769 1.0580 1.0818
BT-20 Torin1
0.37
uM
LJP6
1
O16
72
hr
1097 965 3769 0.2560 -0.0495
BT-20 Torin1
0.37
uM
LJP6
2
O16
72
hr
1097 942 3769 0.2499 -0.0581
BT-20 Torin1
0.37
uM
LJP6
3
O16
72
hr
1097 1111 3769 0.2947 0.0051
BT-20 Torin2
0.37
uM
LJP5
1
I22
72
hr
1097 719 3769 0.1907 -0.1416
BT-20 Torin2
0.37
uM
LJP5
2
I22
72
hr
1097 801 3769 0.2125 -0.1109
BT-20 Torin2
0.37
uM
LJP5
3
I22
72
hr
1097 794 3769 0.2106 -0.1135
BT-20 Tozasertib
0.37
uM
LJP5
1
B16
72
hr
1097 1193 3769 0.3165 0.0358