LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Tozasertib
0.37
uM
LJP5
 2
B16
 72
hr
 1097 1172 3769 0.3109 0.0280
BT-20 Tozasertib
0.37
uM
LJP5
 3
B16
 72
hr
 1097 1223 3769 0.3244 0.0471
BT-20 Trametinib
0.37
uM
LJP5
 1
P22
 72
hr
 1097 2913 3769 0.7728 0.6795
BT-20 Trametinib
0.37
uM
LJP5
 2
P22
 72
hr
 1097 2936 3769 0.7789 0.6881
BT-20 Trametinib
0.37
uM
LJP5
 3
P22
 72
hr
 1097 2735 3769 0.7256 0.6129
BT-20 TWS119
0.37
uM
LJP5
 1
M04
 72
hr
 1097 3207 3769 0.8508 0.7895
BT-20 TWS119
0.37
uM
LJP5
 2
M04
 72
hr
 1097 4067 3769 1.0789 1.1113
BT-20 TWS119
0.37
uM
LJP5
 3
M04
 72
hr
 1097 3422 3769 0.9078 0.8700
BT-20 Vemurafenib
0.37
uM
LJP5
 1
C16
 72
hr
 1097 3646 3769 0.9672 0.9538
BT-20 Vemurafenib
0.37
uM
LJP5
 2
C16
 72
hr
 1097 3558 3769 0.9439 0.9208
BT-20 Vemurafenib
0.37
uM
LJP5
 3
C16
 72
hr
 1097 3544 3769 0.9402 0.9156
BT-20 Withaferin A
0.37
uM
LJP5
 1
G16
 72
hr
 1097 2831 3769 0.7510 0.6488
BT-20 Withaferin A
0.37
uM
LJP5
 2
G16
 72
hr
 1097 2882 3769 0.7646 0.6679
BT-20 Withaferin A
0.37
uM
LJP5
 3
G16
 72
hr
 1097 2671 3769 0.7086 0.5889
BT-20 Withaferin A
0.37
uM
LJP6
 1
G16
 72
hr
 1097 2401 3769 0.6370 0.4879
BT-20 Withaferin A
0.37
uM
LJP6
 2
G16
 72
hr
 1097 2239 3769 0.5940 0.4273
BT-20 Withaferin A
0.37
uM
LJP6
 3
G16
 72
hr
 1097 2141 3769 0.5680 0.3906
BT-20 WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 1097 1287 3769 0.3414 0.0710
BT-20 WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 1097 1303 3769 0.3457 0.0770
BT-20 WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 1097 1369 3769 0.3632 0.1017
BT-20 WZ3105
0.37
uM
LJP5
 1
D22
 72
hr
 1097 1100 3769 0.2918 0.0010
BT-20 WZ3105
0.37
uM
LJP5
 2
D22
 72
hr
 1097 1120 3769 0.2971 0.0085
BT-20 WZ3105
0.37
uM
LJP5
 3
D22
 72
hr
 1097 1209 3769 0.3207 0.0418
BT-20 XMD11-50
0.37
uM
LJP6
 1
P10
 72
hr
 1097 2346 3769 0.6224 0.4673
BT-20 XMD11-50
0.37
uM
LJP6
 2
P10
 72
hr
 1097 2660 3769 0.7057 0.5848