LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 XMD11-50
0.37
uM
LJP6
 3
P10
 72
hr
 1097 2857 3769 0.7579 0.6585
BT-20 Y39983
0.37
uM
LJP6
 1
P04
 72
hr
 1097 3271 3769 0.8678 0.8134
BT-20 Y39983
0.37
uM
LJP6
 2
P04
 72
hr
 1097 3544 3769 0.9402 0.9156
BT-20 Y39983
0.37
uM
LJP6
 3
P04
 72
hr
 1097 3591 3769 0.9526 0.9332
BT-20 YM 201636
0.37
uM
LJP5
 1
N10
 72
hr
 1097 3619 3769 0.9601 0.9437
BT-20 YM 201636
0.37
uM
LJP5
 2
N10
 72
hr
 1097 3893 3769 1.0328 1.0462
BT-20 YM 201636
0.37
uM
LJP5
 3
N10
 72
hr
 1097 3566 3769 0.9460 0.9238
BT-20 ZSTK474
0.37
uM
LJP6
 1
M16
 72
hr
 1097 2009 3769 0.5330 0.3412
BT-20 ZSTK474
0.37
uM
LJP6
 2
M16
 72
hr
 1097 1822 3769 0.4834 0.2712
BT-20 ZSTK474
0.37
uM
LJP6
 3
M16
 72
hr
 1097 2106 3769 0.5587 0.3775
BT-20 Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 1097 3040 3769 0.8065 0.7270
BT-20 Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 1097 3199 3769 0.8487 0.7865
BT-20 Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 1097 3219 3769 0.8540 0.7940
BT-20 Sigma A6730
1.11
uM
LJP5
 1
B21
 72
hr
 1097 3022 3769 0.8017 0.7203
BT-20 Sigma A6730
1.11
uM
LJP5
 2
B21
 72
hr
 1097 3615 3769 0.9590 0.9422
BT-20 Sigma A6730
1.11
uM
LJP5
 3
B21
 72
hr
 1097 3370 3769 0.8940 0.8505
BT-20 Alvocidib
1.11
uM
LJP6
 1
A15
 72
hr
 1097 535 3769 0.1419 -0.2104
BT-20 Alvocidib
1.11
uM
LJP6
 2
A15
 72
hr
 1097 674 3769 0.1788 -0.1584
BT-20 Alvocidib
1.11
uM
LJP6
 3
A15
 72
hr
 1097 627 3769 0.1663 -0.1760
BT-20 AT-7519
1.11
uM
LJP6
 1
K03
 72
hr
 1097 522 3769 0.1385 -0.2153
BT-20 AT-7519
1.11
uM
LJP6
 2
K03
 72
hr
 1097 569 3769 0.1510 -0.1977
BT-20 AT-7519
1.11
uM
LJP6
 3
K03
 72
hr
 1097 673 3769 0.1785 -0.1588
BT-20 AZD 5438
1.11
uM
LJP6
 1
J03
 72
hr
 1097 966 3769 0.2563 -0.0491
BT-20 AZD 5438
1.11
uM
LJP6
 2
J03
 72
hr
 1097 1013 3769 0.2687 -0.0315
BT-20 AZD 5438
1.11
uM
LJP6
 3
J03
 72
hr
 1097 1088 3769 0.2886 -0.0035