LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 BMS345541
0.37
uM
LJP6
3
D04
72
hr
1097 3509 3769 0.9309 0.9025
BT-20 SNS-032
0.37
uM
LJP6
1
H16
72
hr
1097 641 3769 0.1701 -0.1707
BT-20 SNS-032
0.37
uM
LJP6
2
H16
72
hr
1097 672 3769 0.1783 -0.1591
BT-20 SNS-032
0.37
uM
LJP6
3
H16
72
hr
1097 760 3769 0.2016 -0.1262
BT-20 GDC-0980
0.37
uM
LJP5
1
K22
72
hr
1097 891 3769 0.2364 -0.0772
BT-20 GDC-0980
0.37
uM
LJP5
2
K22
72
hr
1097 859 3769 0.2279 -0.0892
BT-20 GDC-0980
0.37
uM
LJP5
3
K22
72
hr
1097 856 3769 0.2271 -0.0903
BT-20 NVP-AEW541
0.37
uM
LJP5
1
E16
72
hr
1097 3821 3769 1.0137 1.0193
BT-20 NVP-AEW541
0.37
uM
LJP5
2
E16
72
hr
1097 3867 3769 1.0259 1.0365
BT-20 NVP-AEW541
0.37
uM
LJP5
3
E16
72
hr
1097 3892 3769 1.0325 1.0458
BT-20 SB590885
0.37
uM
LJP5
1
L16
72
hr
1097 3975 3769 1.0545 1.0769
BT-20 SB590885
0.37
uM
LJP5
2
L16
72
hr
1097 4136 3769 1.0972 1.1371
BT-20 SB590885
0.37
uM
LJP5
3
L16
72
hr
1097 3743 3769 0.9930 0.9901
BT-20 PIK-93
0.37
uM
LJP5
1
K16
72
hr
1097 3834 3769 1.0171 1.0241
BT-20 PIK-93
0.37
uM
LJP5
2
K16
72
hr
1097 4108 3769 1.0898 1.1267
BT-20 PIK-93
0.37
uM
LJP5
3
K16
72
hr
1097 3692 3769 0.9794 0.9710
BT-20 KIN001-043
0.37
uM
LJP6
1
C10
72
hr
1097 3599 3769 0.9548 0.9362
BT-20 KIN001-043
0.37
uM
LJP6
2
C10
72
hr
1097 3578 3769 0.9492 0.9283
BT-20 KIN001-043
0.37
uM
LJP6
3
C10
72
hr
1097 3709 3769 0.9839 0.9774
BT-20 Alpelisib
0.37
uM
LJP5
1
N04
72
hr
1097 2943 3769 0.7807 0.6907
BT-20 Alpelisib
0.37
uM
LJP5
2
N04
72
hr
1097 3383 3769 0.8975 0.8554
BT-20 Alpelisib
0.37
uM
LJP5
3
N04
72
hr
1097 2546 3769 0.6754 0.5421
BT-20 Luminespib
0.37
uM
LJP5
1
H16
72
hr
1097 1111 3769 0.2947 0.0051
BT-20 Luminespib
0.37
uM
LJP5
2
H16
72
hr
1097 1218 3769 0.3231 0.0452
BT-20 Luminespib
0.37
uM
LJP5
3
H16
72
hr
1097 1057 3769 0.2804 -0.0151