LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Imatinib
0.04
uM
LJP6
2
N18
72
hr
1097 3624 3769 0.9614 0.9455
BT-20 Imatinib
0.04
uM
LJP6
3
N18
72
hr
1097 3858 3769 1.0235 1.0331
BT-20 JNK-9L
0.04
uM
LJP6
1
K24
72
hr
1097 3125 3769 0.8290 0.7588
BT-20 JNK-9L
0.04
uM
LJP6
2
K24
72
hr
1097 2724 3769 0.7226 0.6088
BT-20 JNK-9L
0.04
uM
LJP6
3
K24
72
hr
1097 3114 3769 0.8261 0.7547
BT-20 JW-7-24-1
0.04
uM
LJP6
1
B24
72
hr
1097 3130 3769 0.8303 0.7607
BT-20 JW-7-24-1
0.04
uM
LJP6
2
B24
72
hr
1097 2847 3769 0.7553 0.6548
BT-20 JW-7-24-1
0.04
uM
LJP6
3
B24
72
hr
1097 2914 3769 0.7730 0.6799
BT-20 Lapatinib
0.04
uM
LJP6
1
M24
72
hr
1097 3228 3769 0.8563 0.7974
BT-20 Lapatinib
0.04
uM
LJP6
2
M24
72
hr
1097 2936 3769 0.7789 0.6881
BT-20 Lapatinib
0.04
uM
LJP6
3
M24
72
hr
1097 2584 3769 0.6855 0.5564
BT-20 LDN-193189
0.04
uM
LJP5
1
G06
72
hr
1097 3580 3769 0.9497 0.9291
BT-20 LDN-193189
0.04
uM
LJP5
2
G06
72
hr
1097 4047 3769 1.0736 1.1038
BT-20 LDN-193189
0.04
uM
LJP5
3
G06
72
hr
1097 3794 3769 1.0065 1.0092
BT-20 Linifanib
0.04
uM
LJP6
1
J12
72
hr
1097 4076 3769 1.0813 1.1147
BT-20 Linifanib
0.04
uM
LJP6
2
J12
72
hr
1097 3969 3769 1.0529 1.0746
BT-20 Linifanib
0.04
uM
LJP6
3
J12
72
hr
1097 3807 3769 1.0099 1.0140
BT-20 Linsitinib
0.04
uM
LJP5
1
O24
72
hr
1097 3134 3769 0.8314 0.7622
BT-20 Linsitinib
0.04
uM
LJP5
2
O24
72
hr
1097 3674 3769 0.9747 0.9643
BT-20 Linsitinib
0.04
uM
LJP5
3
O24
72
hr
1097 3501 3769 0.9288 0.8995
BT-20 Mitoxantrone
0.04
uM
LJP5
1
C24
72
hr
1097 1374 3769 0.3645 0.1036
BT-20 Mitoxantrone
0.04
uM
LJP5
2
C24
72
hr
1097 1438 3769 0.3815 0.1275
BT-20 Mitoxantrone
0.04
uM
LJP5
3
C24
72
hr
1097 1567 3769 0.4157 0.1758
BT-20 Mitoxantrone
0.04
uM
LJP6
1
C24
72
hr
1097 1587 3769 0.4210 0.1833
BT-20 Mitoxantrone
0.04
uM
LJP6
2
C24
72
hr
1097 1243 3769 0.3298 0.0545