LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Mitoxantrone
0.04
uM
LJP6
3
C24
72
hr
1097 1382 3769 0.3666 0.1066
BT-20 MK2206
0.04
uM
LJP6
1
F06
72
hr
1097 3405 3769 0.9033 0.8636
BT-20 MK2206
0.04
uM
LJP6
2
F06
72
hr
1097 3164 3769 0.8394 0.7734
BT-20 MK2206
0.04
uM
LJP6
3
F06
72
hr
1097 3308 3769 0.8776 0.8273
BT-20 Neratinib
0.04
uM
LJP5
1
A18
72
hr
1097 2621 3769 0.6953 0.5702
BT-20 Neratinib
0.04
uM
LJP5
2
A18
72
hr
1097 2956 3769 0.7842 0.6956
BT-20 Neratinib
0.04
uM
LJP5
3
A18
72
hr
1097 3103 3769 0.8232 0.7506
BT-20 Nilotinib
0.04
uM
LJP5
1
N18
72
hr
1097 4017 3769 1.0656 1.0926
BT-20 Nilotinib
0.04
uM
LJP5
2
N18
72
hr
1097 4097 3769 1.0869 1.1225
BT-20 Nilotinib
0.04
uM
LJP5
3
N18
72
hr
1097 3777 3769 1.0020 1.0028
BT-20 Nintedanib
0.04
uM
LJP6
1
H06
72
hr
1097 3683 3769 0.9770 0.9676
BT-20 Nintedanib
0.04
uM
LJP6
2
H06
72
hr
1097 3458 3769 0.9174 0.8834
BT-20 Nintedanib
0.04
uM
LJP6
3
H06
72
hr
1097 3539 3769 0.9388 0.9137
BT-20 NU7441
0.04
uM
LJP5
1
C12
72
hr
1097 4382 3769 1.1625 1.2292
BT-20 NU7441
0.04
uM
LJP5
2
C12
72
hr
1097 3846 3769 1.0203 1.0286
BT-20 NU7441
0.04
uM
LJP5
3
C12
72
hr
1097 4131 3769 1.0959 1.1353
BT-20 Dactolisib
0.04
uM
LJP5
1
M18
72
hr
1097 1456 3769 0.3863 0.1343
BT-20 Dactolisib
0.04
uM
LJP5
2
M18
72
hr
1097 1381 3769 0.3664 0.1062
BT-20 Dactolisib
0.04
uM
LJP5
3
M18
72
hr
1097 1339 3769 0.3552 0.0905
BT-20 NVP-TAE684
0.04
uM
LJP6
1
K18
72
hr
1097 3798 3769 1.0076 1.0107
BT-20 NVP-TAE684
0.04
uM
LJP6
2
K18
72
hr
1097 3756 3769 0.9964 0.9949
BT-20 NVP-TAE684
0.04
uM
LJP6
3
K18
72
hr
1097 3806 3769 1.0097 1.0136
BT-20 Palbociclib
0.04
uM
LJP6
1
E18
72
hr
1097 2447 3769 0.6492 0.5051
BT-20 Palbociclib
0.04
uM
LJP6
2
E18
72
hr
1097 2381 3769 0.6316 0.4804
BT-20 Palbociclib
0.04
uM
LJP6
3
E18
72
hr
1097 2433 3769 0.6454 0.4999