LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
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BT-20 | Mitoxantrone | 0.04 | uM | LJP6 | 3 | C24 | 72 | hr | 1097 | 1382 | 3769 | 0.3666 | 0.1066 |
BT-20 | MK2206 | 0.04 | uM | LJP6 | 1 | F06 | 72 | hr | 1097 | 3405 | 3769 | 0.9033 | 0.8636 |
BT-20 | MK2206 | 0.04 | uM | LJP6 | 2 | F06 | 72 | hr | 1097 | 3164 | 3769 | 0.8394 | 0.7734 |
BT-20 | MK2206 | 0.04 | uM | LJP6 | 3 | F06 | 72 | hr | 1097 | 3308 | 3769 | 0.8776 | 0.8273 |
BT-20 | Neratinib | 0.04 | uM | LJP5 | 1 | A18 | 72 | hr | 1097 | 2621 | 3769 | 0.6953 | 0.5702 |
BT-20 | Neratinib | 0.04 | uM | LJP5 | 2 | A18 | 72 | hr | 1097 | 2956 | 3769 | 0.7842 | 0.6956 |
BT-20 | Neratinib | 0.04 | uM | LJP5 | 3 | A18 | 72 | hr | 1097 | 3103 | 3769 | 0.8232 | 0.7506 |
BT-20 | Nilotinib | 0.04 | uM | LJP5 | 1 | N18 | 72 | hr | 1097 | 4017 | 3769 | 1.0656 | 1.0926 |
BT-20 | Nilotinib | 0.04 | uM | LJP5 | 2 | N18 | 72 | hr | 1097 | 4097 | 3769 | 1.0869 | 1.1225 |
BT-20 | Nilotinib | 0.04 | uM | LJP5 | 3 | N18 | 72 | hr | 1097 | 3777 | 3769 | 1.0020 | 1.0028 |
BT-20 | Nintedanib | 0.04 | uM | LJP6 | 1 | H06 | 72 | hr | 1097 | 3683 | 3769 | 0.9770 | 0.9676 |
BT-20 | Nintedanib | 0.04 | uM | LJP6 | 2 | H06 | 72 | hr | 1097 | 3458 | 3769 | 0.9174 | 0.8834 |
BT-20 | Nintedanib | 0.04 | uM | LJP6 | 3 | H06 | 72 | hr | 1097 | 3539 | 3769 | 0.9388 | 0.9137 |
BT-20 | NU7441 | 0.04 | uM | LJP5 | 1 | C12 | 72 | hr | 1097 | 4382 | 3769 | 1.1625 | 1.2292 |
BT-20 | NU7441 | 0.04 | uM | LJP5 | 2 | C12 | 72 | hr | 1097 | 3846 | 3769 | 1.0203 | 1.0286 |
BT-20 | NU7441 | 0.04 | uM | LJP5 | 3 | C12 | 72 | hr | 1097 | 4131 | 3769 | 1.0959 | 1.1353 |
BT-20 | Dactolisib | 0.04 | uM | LJP5 | 1 | M18 | 72 | hr | 1097 | 1456 | 3769 | 0.3863 | 0.1343 |
BT-20 | Dactolisib | 0.04 | uM | LJP5 | 2 | M18 | 72 | hr | 1097 | 1381 | 3769 | 0.3664 | 0.1062 |
BT-20 | Dactolisib | 0.04 | uM | LJP5 | 3 | M18 | 72 | hr | 1097 | 1339 | 3769 | 0.3552 | 0.0905 |
BT-20 | NVP-TAE684 | 0.04 | uM | LJP6 | 1 | K18 | 72 | hr | 1097 | 3798 | 3769 | 1.0076 | 1.0107 |
BT-20 | NVP-TAE684 | 0.04 | uM | LJP6 | 2 | K18 | 72 | hr | 1097 | 3756 | 3769 | 0.9964 | 0.9949 |
BT-20 | NVP-TAE684 | 0.04 | uM | LJP6 | 3 | K18 | 72 | hr | 1097 | 3806 | 3769 | 1.0097 | 1.0136 |
BT-20 | Palbociclib | 0.04 | uM | LJP6 | 1 | E18 | 72 | hr | 1097 | 2447 | 3769 | 0.6492 | 0.5051 |
BT-20 | Palbociclib | 0.04 | uM | LJP6 | 2 | E18 | 72 | hr | 1097 | 2381 | 3769 | 0.6316 | 0.4804 |
BT-20 | Palbociclib | 0.04 | uM | LJP6 | 3 | E18 | 72 | hr | 1097 | 2433 | 3769 | 0.6454 | 0.4999 |