LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | PD184352 | 10.0 | uM | LJP5 | 2 | L07 | 72 | hr | 513 | 797 | 10401 | 0.0766 | 0.0287 |
| MCF 10A | PD184352 | 10.0 | uM | LJP5 | 3 | L07 | 72 | hr | 513 | 785 | 10401 | 0.0755 | 0.0275 |
| MCF 10A | Pelitinib | 10.0 | uM | LJP5 | 1 | I13 | 72 | hr | 513 | 529 | 10401 | 0.0509 | 0.0016 |
| MCF 10A | Pelitinib | 10.0 | uM | LJP5 | 2 | I13 | 72 | hr | 513 | 556 | 10401 | 0.0535 | 0.0043 |
| MCF 10A | Pelitinib | 10.0 | uM | LJP5 | 3 | I13 | 72 | hr | 513 | 465 | 10401 | 0.0447 | -0.0049 |
| MCF 10A | PF431396 | 10.0 | uM | LJP5 | 1 | E07 | 72 | hr | 513 | 557 | 10401 | 0.0536 | 0.0044 |
| MCF 10A | PF431396 | 10.0 | uM | LJP5 | 2 | E07 | 72 | hr | 513 | 694 | 10401 | 0.0667 | 0.0183 |
| MCF 10A | PF431396 | 10.0 | uM | LJP5 | 3 | E07 | 72 | hr | 513 | 526 | 10401 | 0.0506 | 0.0013 |
| MCF 10A | PF477736 | 10.0 | uM | LJP5 | 1 | J19 | 72 | hr | 513 | 560 | 10401 | 0.0538 | 0.0047 |
| MCF 10A | PF477736 | 10.0 | uM | LJP5 | 2 | J19 | 72 | hr | 513 | 670 | 10401 | 0.0644 | 0.0158 |
| MCF 10A | PF477736 | 10.0 | uM | LJP5 | 3 | J19 | 72 | hr | 513 | 570 | 10401 | 0.0548 | 0.0057 |
| MCF 10A | PF562271 | 10.0 | uM | LJP6 | 1 | F13 | 72 | hr | 513 | 623 | 10401 | 0.0599 | 0.0111 |
| MCF 10A | PF562271 | 10.0 | uM | LJP6 | 2 | F13 | 72 | hr | 513 | 561 | 10401 | 0.0539 | 0.0048 |
| MCF 10A | PF562271 | 10.0 | uM | LJP6 | 3 | F13 | 72 | hr | 513 | 585 | 10401 | 0.0562 | 0.0072 |
| MCF 10A | PHA-665752 | 10.0 | uM | LJP5 | 1 | F13 | 72 | hr | 513 | 599 | 10401 | 0.0576 | 0.0087 |
| MCF 10A | PHA-665752 | 10.0 | uM | LJP5 | 2 | F13 | 72 | hr | 513 | 950 | 10401 | 0.0913 | 0.0442 |
| MCF 10A | PHA-665752 | 10.0 | uM | LJP5 | 3 | F13 | 72 | hr | 513 | 503 | 10401 | 0.0484 | -0.0010 |
| MCF 10A | PHA-793887 | 10.0 | uM | LJP6 | 1 | E19 | 72 | hr | 513 | 575 | 10401 | 0.0553 | 0.0062 |
| MCF 10A | PHA-793887 | 10.0 | uM | LJP6 | 2 | E19 | 72 | hr | 513 | 523 | 10401 | 0.0503 | 0.0010 |
| MCF 10A | PHA-793887 | 10.0 | uM | LJP6 | 3 | E19 | 72 | hr | 513 | 603 | 10401 | 0.0580 | 0.0091 |
| MCF 10A | PI103 | 10.0 | uM | LJP6 | 1 | I13 | 72 | hr | 513 | 778 | 10401 | 0.0748 | 0.0268 |
| MCF 10A | PI103 | 10.0 | uM | LJP6 | 2 | I13 | 72 | hr | 513 | 760 | 10401 | 0.0731 | 0.0249 |
| MCF 10A | PI103 | 10.0 | uM | LJP6 | 3 | I13 | 72 | hr | 513 | 779 | 10401 | 0.0749 | 0.0269 |
| MCF 10A | PLX-4720 | 10.0 | uM | LJP5 | 1 | K01 | 72 | hr | 513 | 7440 | 10401 | 0.7153 | 0.7005 |
| MCF 10A | PLX-4720 | 10.0 | uM | LJP5 | 2 | K01 | 72 | hr | 513 | 7066 | 10401 | 0.6794 | 0.6627 |