LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 1235 1841 4156 0.4430 0.2074
MCF7 Gefitinib
0.04
uM
LJP6
 1
N12
 72
hr
 1235 4441 4156 1.0685 1.0975
MCF7 Gefitinib
0.04
uM
LJP6
 2
N12
 72
hr
 1235 4611 4156 1.1094 1.1557
MCF7 Gefitinib
0.04
uM
LJP6
 3
N12
 72
hr
 1235 4809 4156 1.1571 1.2235
MCF7 Geldanamycin
0.04
uM
LJP5
 1
O06
 72
hr
 1235 2211 4156 0.5320 0.3340
MCF7 Geldanamycin
0.04
uM
LJP5
 2
O06
 72
hr
 1235 2210 4156 0.5317 0.3337
MCF7 Geldanamycin
0.04
uM
LJP5
 3
O06
 72
hr
 1235 2403 4156 0.5782 0.3998
MCF7 Geldanamycin
0.04
uM
LJP6
 1
O06
 72
hr
 1235 2466 4156 0.5933 0.4213
MCF7 Geldanamycin
0.04
uM
LJP6
 2
O06
 72
hr
 1235 2286 4156 0.5500 0.3597
MCF7 Geldanamycin
0.04
uM
LJP6
 3
O06
 72
hr
 1235 2645 4156 0.6364 0.4826
MCF7 GSK1059615
0.04
uM
LJP5
 1
E06
 72
hr
 1235 4172 4156 1.0038 1.0054
MCF7 GSK1059615
0.04
uM
LJP5
 2
E06
 72
hr
 1235 4160 4156 1.0009 1.0013
MCF7 GSK1059615
0.04
uM
LJP5
 3
E06
 72
hr
 1235 4534 4156 1.0909 1.1294
MCF7 GSK1059615
0.04
uM
LJP6
 1
C06
 72
hr
 1235 4162 4156 1.0014 1.0020
MCF7 GSK1059615
0.04
uM
LJP6
 2
C06
 72
hr
 1235 4333 4156 1.0425 1.0605
MCF7 GSK1059615
0.04
uM
LJP6
 3
C06
 72
hr
 1235 4003 4156 0.9632 0.9476
MCF7 GSK1904529A
0.04
uM
LJP6
 1
H24
 72
hr
 1235 1966 4156 0.4730 0.2501
MCF7 GSK1904529A
0.04
uM
LJP6
 2
H24
 72
hr
 1235 1909 4156 0.4593 0.2306
MCF7 GSK1904529A
0.04
uM
LJP6
 3
H24
 72
hr
 1235 1984 4156 0.4774 0.2563
MCF7 Omipalisib
0.04
uM
LJP6
 1
N06
 72
hr
 1235 1441 4156 0.3467 0.0704
MCF7 Omipalisib
0.04
uM
LJP6
 2
N06
 72
hr
 1235 1257 4156 0.3024 0.0074
MCF7 Omipalisib
0.04
uM
LJP6
 3
N06
 72
hr
 1235 1389 4156 0.3342 0.0526
MCF7 GSK 690693
0.04
uM
LJP5
 1
F24
 72
hr
 1235 2317 4156 0.5575 0.3703
MCF7 GSK 690693
0.04
uM
LJP5
 2
F24
 72
hr
 1235 2747 4156 0.6610 0.5175
MCF7 GSK 690693
0.04
uM
LJP5
 3
F24
 72
hr
 1235 2901 4156 0.6980 0.5703