LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Nintedanib | 10.0 | uM | LJP6 | 1 | H01 | 72 | hr | 513 | 9271 | 10401 | 0.8913 | 0.8857 |
| MCF 10A | Nintedanib | 10.0 | uM | LJP6 | 2 | H01 | 72 | hr | 513 | 8903 | 10401 | 0.8560 | 0.8485 |
| MCF 10A | Nintedanib | 10.0 | uM | LJP6 | 3 | H01 | 72 | hr | 513 | 8948 | 10401 | 0.8603 | 0.8530 |
| MCF 10A | NU7441 | 10.0 | uM | LJP5 | 1 | C07 | 72 | hr | 513 | 819 | 10401 | 0.0787 | 0.0309 |
| MCF 10A | NU7441 | 10.0 | uM | LJP5 | 2 | C07 | 72 | hr | 513 | 1086 | 10401 | 0.1044 | 0.0579 |
| MCF 10A | NU7441 | 10.0 | uM | LJP5 | 3 | C07 | 72 | hr | 513 | 1103 | 10401 | 0.1061 | 0.0596 |
| MCF 10A | Dactolisib | 10.0 | uM | LJP5 | 1 | M13 | 72 | hr | 513 | 1163 | 10401 | 0.1118 | 0.0657 |
| MCF 10A | Dactolisib | 10.0 | uM | LJP5 | 2 | M13 | 72 | hr | 513 | 1159 | 10401 | 0.1114 | 0.0653 |
| MCF 10A | Dactolisib | 10.0 | uM | LJP5 | 3 | M13 | 72 | hr | 513 | 1149 | 10401 | 0.1105 | 0.0643 |
| MCF 10A | NVP-TAE684 | 10.0 | uM | LJP6 | 1 | K13 | 72 | hr | 513 | 870 | 10401 | 0.0836 | 0.0361 |
| MCF 10A | NVP-TAE684 | 10.0 | uM | LJP6 | 2 | K13 | 72 | hr | 513 | 932 | 10401 | 0.0896 | 0.0423 |
| MCF 10A | NVP-TAE684 | 10.0 | uM | LJP6 | 3 | K13 | 72 | hr | 513 | 787 | 10401 | 0.0757 | 0.0277 |
| MCF 10A | Palbociclib | 10.0 | uM | LJP6 | 1 | E13 | 72 | hr | 513 | 2407 | 10401 | 0.2314 | 0.1915 |
| MCF 10A | Palbociclib | 10.0 | uM | LJP6 | 2 | E13 | 72 | hr | 513 | 2246 | 10401 | 0.2159 | 0.1752 |
| MCF 10A | Palbociclib | 10.0 | uM | LJP6 | 3 | E13 | 72 | hr | 513 | 2532 | 10401 | 0.2434 | 0.2042 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP5 | 1 | C01 | 72 | hr | 513 | 643 | 10401 | 0.0618 | 0.0131 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP5 | 2 | C01 | 72 | hr | 513 | 590 | 10401 | 0.0567 | 0.0078 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP5 | 3 | C01 | 72 | hr | 513 | 492 | 10401 | 0.0473 | -0.0022 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP6 | 1 | E01 | 72 | hr | 513 | 432 | 10401 | 0.0415 | -0.0082 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP6 | 2 | E01 | 72 | hr | 513 | 384 | 10401 | 0.0369 | -0.0131 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP6 | 3 | E01 | 72 | hr | 513 | 378 | 10401 | 0.0363 | -0.0137 |
| MCF 10A | PD173074 | 10.0 | uM | LJP6 | 1 | I07 | 72 | hr | 513 | 3308 | 10401 | 0.3180 | 0.2826 |
| MCF 10A | PD173074 | 10.0 | uM | LJP6 | 2 | I07 | 72 | hr | 513 | 3059 | 10401 | 0.2941 | 0.2575 |
| MCF 10A | PD173074 | 10.0 | uM | LJP6 | 3 | I07 | 72 | hr | 513 | 2609 | 10401 | 0.2508 | 0.2119 |
| MCF 10A | PD184352 | 10.0 | uM | LJP5 | 1 | L07 | 72 | hr | 513 | 763 | 10401 | 0.0734 | 0.0252 |