LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF 10A Torin1
3.33
uM
LJP6
 3
O14
 72
hr
 513 1006 10401 0.0967 0.0498
MCF 10A Torin2
3.33
uM
LJP5
 1
I20
 72
hr
 513 527 10401 0.0507 0.0014
MCF 10A Torin2
3.33
uM
LJP5
 2
I20
 72
hr
 513 449 10401 0.0432 -0.0065
MCF 10A Torin2
3.33
uM
LJP5
 3
I20
 72
hr
 513 611 10401 0.0587 0.0099
MCF 10A Tozasertib
3.33
uM
LJP5
 1
B14
 72
hr
 513 803 10401 0.0772 0.0293
MCF 10A Tozasertib
3.33
uM
LJP5
 2
B14
 72
hr
 513 775 10401 0.0745 0.0265
MCF 10A Tozasertib
3.33
uM
LJP5
 3
B14
 72
hr
 513 1095 10401 0.1053 0.0588
MCF 10A Trametinib
3.33
uM
LJP5
 1
P20
 72
hr
 513 932 10401 0.0896 0.0423
MCF 10A Trametinib
3.33
uM
LJP5
 2
P20
 72
hr
 513 851 10401 0.0818 0.0341
MCF 10A Trametinib
3.33
uM
LJP5
 3
P20
 72
hr
 513 948 10401 0.0911 0.0440
MCF 10A TWS119
3.33
uM
LJP5
 1
M02
 72
hr
 513 6641 10401 0.6385 0.6197
MCF 10A TWS119
3.33
uM
LJP5
 2
M02
 72
hr
 513 6381 10401 0.6135 0.5934
MCF 10A TWS119
3.33
uM
LJP5
 3
M02
 72
hr
 513 6291 10401 0.6048 0.5843
MCF 10A Vemurafenib
3.33
uM
LJP5
 1
C14
 72
hr
 513 3867 10401 0.3718 0.3392
MCF 10A Vemurafenib
3.33
uM
LJP5
 2
C14
 72
hr
 513 4101 10401 0.3943 0.3628
MCF 10A Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 513 5325 10401 0.5120 0.4866
MCF 10A Withaferin A
3.33
uM
LJP5
 1
G14
 72
hr
 513 355 10401 0.0341 -0.0160
MCF 10A Withaferin A
3.33
uM
LJP5
 2
G14
 72
hr
 513 405 10401 0.0389 -0.0110
MCF 10A Withaferin A
3.33
uM
LJP5
 3
G14
 72
hr
 513 364 10401 0.0350 -0.0151
MCF 10A Withaferin A
3.33
uM
LJP6
 1
G14
 72
hr
 513 290 10401 0.0279 -0.0226
MCF 10A Withaferin A
3.33
uM
LJP6
 2
G14
 72
hr
 513 369 10401 0.0355 -0.0146
MCF 10A Withaferin A
3.33
uM
LJP6
 3
G14
 72
hr
 513 377 10401 0.0362 -0.0138
MCF 10A WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 513 917 10401 0.0882 0.0408
MCF 10A WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 513 903 10401 0.0868 0.0394
MCF 10A WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 513 869 10401 0.0835 0.0360