LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | PLX-4720 | 10.0 | uM | LJP5 | 3 | K01 | 72 | hr | 513 | 6900 | 10401 | 0.6634 | 0.6459 |
| MCF 10A | QL-X-138 | 10.0 | uM | LJP6 | 1 | F19 | 72 | hr | 513 | 326 | 10401 | 0.0313 | -0.0189 |
| MCF 10A | QL-X-138 | 10.0 | uM | LJP6 | 2 | F19 | 72 | hr | 513 | 365 | 10401 | 0.0351 | -0.0150 |
| MCF 10A | QL-X-138 | 10.0 | uM | LJP6 | 3 | F19 | 72 | hr | 513 | 398 | 10401 | 0.0383 | -0.0117 |
| MCF 10A | QL-XII-47 | 10.0 | uM | LJP6 | 1 | O19 | 72 | hr | 513 | 623 | 10401 | 0.0599 | 0.0111 |
| MCF 10A | QL-XII-47 | 10.0 | uM | LJP6 | 2 | O19 | 72 | hr | 513 | 576 | 10401 | 0.0554 | 0.0063 |
| MCF 10A | QL-XII-47 | 10.0 | uM | LJP6 | 3 | O19 | 72 | hr | 513 | 502 | 10401 | 0.0483 | -0.0011 |
| MCF 10A | Radicicol | 10.0 | uM | LJP5 | 1 | K07 | 72 | hr | 513 | 408 | 10401 | 0.0392 | -0.0107 |
| MCF 10A | Radicicol | 10.0 | uM | LJP5 | 2 | K07 | 72 | hr | 513 | 351 | 10401 | 0.0337 | -0.0164 |
| MCF 10A | Radicicol | 10.0 | uM | LJP5 | 3 | K07 | 72 | hr | 513 | 284 | 10401 | 0.0273 | -0.0232 |
| MCF 10A | Radicicol | 10.0 | uM | LJP6 | 1 | K07 | 72 | hr | 513 | 429 | 10401 | 0.0412 | -0.0085 |
| MCF 10A | Radicicol | 10.0 | uM | LJP6 | 2 | K07 | 72 | hr | 513 | 454 | 10401 | 0.0436 | -0.0060 |
| MCF 10A | Radicicol | 10.0 | uM | LJP6 | 3 | K07 | 72 | hr | 513 | 374 | 10401 | 0.0360 | -0.0141 |
| MCF 10A | Seliciclib | 10.0 | uM | LJP5 | 1 | J01 | 72 | hr | 513 | 1052 | 10401 | 0.1011 | 0.0545 |
| MCF 10A | Seliciclib | 10.0 | uM | LJP5 | 2 | J01 | 72 | hr | 513 | 1230 | 10401 | 0.1183 | 0.0725 |
| MCF 10A | Seliciclib | 10.0 | uM | LJP5 | 3 | J01 | 72 | hr | 513 | 1525 | 10401 | 0.1466 | 0.1023 |
| MCF 10A | Ruxolitinib | 10.0 | uM | LJP5 | 1 | O13 | 72 | hr | 513 | 6898 | 10401 | 0.6632 | 0.6457 |
| MCF 10A | Ruxolitinib | 10.0 | uM | LJP5 | 2 | O13 | 72 | hr | 513 | 7060 | 10401 | 0.6788 | 0.6621 |
| MCF 10A | Ruxolitinib | 10.0 | uM | LJP5 | 3 | O13 | 72 | hr | 513 | 6059 | 10401 | 0.5825 | 0.5609 |
| MCF 10A | XL147 | 10.0 | uM | LJP5 | 1 | G07 | 72 | hr | 513 | 4217 | 10401 | 0.4054 | 0.3746 |
| MCF 10A | XL147 | 10.0 | uM | LJP5 | 2 | G07 | 72 | hr | 513 | 4851 | 10401 | 0.4664 | 0.4387 |
| MCF 10A | XL147 | 10.0 | uM | LJP5 | 3 | G07 | 72 | hr | 513 | 5254 | 10401 | 0.5051 | 0.4794 |
| MCF 10A | Saracatinib | 10.0 | uM | LJP6 | 1 | D07 | 72 | hr | 513 | 741 | 10401 | 0.0712 | 0.0230 |
| MCF 10A | Saracatinib | 10.0 | uM | LJP6 | 2 | D07 | 72 | hr | 513 | 696 | 10401 | 0.0669 | 0.0185 |
| MCF 10A | Saracatinib | 10.0 | uM | LJP6 | 3 | D07 | 72 | hr | 513 | 713 | 10401 | 0.0686 | 0.0202 |