LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | AT-7519 | 10.0 | uM | LJP6 | 2 | K01 | 72 | hr | 513 | 465 | 10401 | 0.0447 | -0.0049 |
| MCF 10A | AT-7519 | 10.0 | uM | LJP6 | 3 | K01 | 72 | hr | 513 | 545 | 10401 | 0.0524 | 0.0032 |
| MCF 10A | AZD 5438 | 10.0 | uM | LJP6 | 1 | J01 | 72 | hr | 513 | 593 | 10401 | 0.0570 | 0.0081 |
| MCF 10A | AZD 5438 | 10.0 | uM | LJP6 | 2 | J01 | 72 | hr | 513 | 581 | 10401 | 0.0559 | 0.0068 |
| MCF 10A | AZD 5438 | 10.0 | uM | LJP6 | 3 | J01 | 72 | hr | 513 | 555 | 10401 | 0.0534 | 0.0042 |
| MCF 10A | AZD-6482 | 10.0 | uM | LJP5 | 1 | I01 | 72 | hr | 513 | 778 | 10401 | 0.0748 | 0.0268 |
| MCF 10A | AZD-6482 | 10.0 | uM | LJP5 | 2 | I01 | 72 | hr | 513 | 670 | 10401 | 0.0644 | 0.0158 |
| MCF 10A | AZD-6482 | 10.0 | uM | LJP5 | 3 | I01 | 72 | hr | 513 | 871 | 10401 | 0.0837 | 0.0362 |
| MCF 10A | AZD7762 | 10.0 | uM | LJP6 | 1 | L01 | 72 | hr | 513 | 352 | 10401 | 0.0338 | -0.0163 |
| MCF 10A | AZD7762 | 10.0 | uM | LJP6 | 2 | L01 | 72 | hr | 513 | 375 | 10401 | 0.0361 | -0.0140 |
| MCF 10A | AZD7762 | 10.0 | uM | LJP6 | 3 | L01 | 72 | hr | 513 | 334 | 10401 | 0.0321 | -0.0181 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 513 | 887 | 10401 | 0.0853 | 0.0378 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 513 | 872 | 10401 | 0.0838 | 0.0363 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 513 | 761 | 10401 | 0.0732 | 0.0250 |
| MCF 10A | AZD8330 | 10.0 | uM | LJP5 | 1 | G19 | 72 | hr | 513 | 562 | 10401 | 0.0540 | 0.0049 |
| MCF 10A | AZD8330 | 10.0 | uM | LJP5 | 2 | G19 | 72 | hr | 513 | 573 | 10401 | 0.0551 | 0.0060 |
| MCF 10A | AZD8330 | 10.0 | uM | LJP5 | 3 | G19 | 72 | hr | 513 | 597 | 10401 | 0.0574 | 0.0085 |
| MCF 10A | Barasertib | 10.0 | uM | LJP5 | 1 | D07 | 72 | hr | 513 | 1286 | 10401 | 0.1236 | 0.0781 |
| MCF 10A | Barasertib | 10.0 | uM | LJP5 | 2 | D07 | 72 | hr | 513 | 1230 | 10401 | 0.1183 | 0.0725 |
| MCF 10A | Barasertib | 10.0 | uM | LJP5 | 3 | D07 | 72 | hr | 513 | 1406 | 10401 | 0.1352 | 0.0903 |
| MCF 10A | BI-2536 | 10.0 | uM | LJP6 | 1 | D13 | 72 | hr | 513 | 823 | 10401 | 0.0791 | 0.0313 |
| MCF 10A | BI-2536 | 10.0 | uM | LJP6 | 2 | D13 | 72 | hr | 513 | 677 | 10401 | 0.0651 | 0.0165 |
| MCF 10A | BI-2536 | 10.0 | uM | LJP6 | 3 | D13 | 72 | hr | 513 | 782 | 10401 | 0.0752 | 0.0272 |
| MCF 10A | BMS345541 | 10.0 | uM | LJP6 | 1 | D01 | 72 | hr | 513 | 7641 | 10401 | 0.7346 | 0.7209 |
| MCF 10A | BMS345541 | 10.0 | uM | LJP6 | 2 | D01 | 72 | hr | 513 | 7482 | 10401 | 0.7193 | 0.7048 |