LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF 10A CP724714
3.33
uM
LJP5
 1
A08
 72
hr
 513 9901 10401 0.9519 0.9494
MCF 10A CP724714
3.33
uM
LJP5
 2
A08
 72
hr
 513 10199 10401 0.9806 0.9796
MCF 10A CP724714
3.33
uM
LJP5
 3
A08
 72
hr
 513 10092 10401 0.9703 0.9687
MCF 10A CP466722
3.33
uM
LJP5
 1
I08
 72
hr
 513 9152 10401 0.8799 0.8737
MCF 10A CP466722
3.33
uM
LJP5
 2
I08
 72
hr
 513 9995 10401 0.9610 0.9589
MCF 10A CP466722
3.33
uM
LJP5
 3
I08
 72
hr
 513 9405 10401 0.9042 0.8993
MCF 10A Crizotinib
3.33
uM
LJP5
 1
A20
 72
hr
 513 6173 10401 0.5935 0.5724
MCF 10A Crizotinib
3.33
uM
LJP5
 2
A20
 72
hr
 513 7290 10401 0.7009 0.6854
MCF 10A Crizotinib
3.33
uM
LJP5
 3
A20
 72
hr
 513 6324 10401 0.6080 0.5877
MCF 10A Momelotinib
3.33
uM
LJP5
 1
P08
 72
hr
 513 3897 10401 0.3747 0.3422
MCF 10A Momelotinib
3.33
uM
LJP5
 2
P08
 72
hr
 513 4411 10401 0.4241 0.3942
MCF 10A Momelotinib
3.33
uM
LJP5
 3
P08
 72
hr
 513 4678 10401 0.4498 0.4212
MCF 10A Dasatinib
3.33
uM
LJP5
 1
D02
 72
hr
 513 303 10401 0.0291 -0.0213
MCF 10A Dasatinib
3.33
uM
LJP5
 2
D02
 72
hr
 513 324 10401 0.0312 -0.0192
MCF 10A Dasatinib
3.33
uM
LJP5
 3
D02
 72
hr
 513 385 10401 0.0370 -0.0130
MCF 10A Dasatinib
3.33
uM
LJP6
 1
I02
 72
hr
 513 320 10401 0.0308 -0.0196
MCF 10A Dasatinib
3.33
uM
LJP6
 2
I02
 72
hr
 513 254 10401 0.0244 -0.0262
MCF 10A Dasatinib
3.33
uM
LJP6
 3
I02
 72
hr
 513 341 10401 0.0328 -0.0174
MCF 10A Dovitinib
3.33
uM
LJP5
 1
E20
 72
hr
 513 1355 10401 0.1303 0.0851
MCF 10A Dovitinib
3.33
uM
LJP5
 2
E20
 72
hr
 513 660 10401 0.0635 0.0148
MCF 10A Dovitinib
3.33
uM
LJP5
 3
E20
 72
hr
 513 1205 10401 0.1159 0.0699
MCF 10A Enzastaurin
3.33
uM
LJP5
 1
D14
 72
hr
 513 9129 10401 0.8777 0.8713
MCF 10A Enzastaurin
3.33
uM
LJP5
 2
D14
 72
hr
 513 8367 10401 0.8044 0.7943
MCF 10A Enzastaurin
3.33
uM
LJP5
 3
D14
 72
hr
 513 9942 10401 0.9559 0.9536
MCF 10A Erlotinib
3.33
uM
LJP5
 1
M20
 72
hr
 513 616 10401 0.0592 0.0104