LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Mitoxantrone | 1.11 | uM | LJP6 | 3 | C21 | 72 | hr | 513 | 399 | 10401 | 0.0384 | -0.0116 |
| MCF 10A | MK2206 | 1.11 | uM | LJP6 | 1 | F03 | 72 | hr | 513 | 7785 | 10401 | 0.7485 | 0.7354 |
| MCF 10A | MK2206 | 1.11 | uM | LJP6 | 2 | F03 | 72 | hr | 513 | 6827 | 10401 | 0.6564 | 0.6385 |
| MCF 10A | MK2206 | 1.11 | uM | LJP6 | 3 | F03 | 72 | hr | 513 | 7213 | 10401 | 0.6935 | 0.6776 |
| MCF 10A | Neratinib | 1.11 | uM | LJP5 | 1 | A15 | 72 | hr | 513 | 864 | 10401 | 0.0831 | 0.0355 |
| MCF 10A | Neratinib | 1.11 | uM | LJP5 | 2 | A15 | 72 | hr | 513 | 684 | 10401 | 0.0658 | 0.0173 |
| MCF 10A | Neratinib | 1.11 | uM | LJP5 | 3 | A15 | 72 | hr | 513 | 589 | 10401 | 0.0566 | 0.0076 |
| MCF 10A | Nilotinib | 1.11 | uM | LJP5 | 1 | N15 | 72 | hr | 513 | 10906 | 10401 | 1.0485 | 1.0511 |
| MCF 10A | Nilotinib | 1.11 | uM | LJP5 | 2 | N15 | 72 | hr | 513 | 11146 | 10401 | 1.0716 | 1.0753 |
| MCF 10A | Nilotinib | 1.11 | uM | LJP5 | 3 | N15 | 72 | hr | 513 | 10603 | 10401 | 1.0194 | 1.0204 |
| MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 1 | H03 | 72 | hr | 513 | 10802 | 10401 | 1.0385 | 1.0405 |
| MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 2 | H03 | 72 | hr | 513 | 10380 | 10401 | 0.9980 | 0.9979 |
| MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 3 | H03 | 72 | hr | 513 | 10195 | 10401 | 0.9802 | 0.9792 |
| MCF 10A | NU7441 | 1.11 | uM | LJP5 | 1 | C09 | 72 | hr | 513 | 8931 | 10401 | 0.8587 | 0.8513 |
| MCF 10A | NU7441 | 1.11 | uM | LJP5 | 2 | C09 | 72 | hr | 513 | 9512 | 10401 | 0.9145 | 0.9101 |
| MCF 10A | NU7441 | 1.11 | uM | LJP5 | 3 | C09 | 72 | hr | 513 | 9304 | 10401 | 0.8945 | 0.8890 |
| MCF 10A | Dactolisib | 1.11 | uM | LJP5 | 1 | M15 | 72 | hr | 513 | 876 | 10401 | 0.0842 | 0.0367 |
| MCF 10A | Dactolisib | 1.11 | uM | LJP5 | 2 | M15 | 72 | hr | 513 | 1108 | 10401 | 0.1065 | 0.0601 |
| MCF 10A | Dactolisib | 1.11 | uM | LJP5 | 3 | M15 | 72 | hr | 513 | 990 | 10401 | 0.0952 | 0.0482 |
| MCF 10A | NVP-TAE684 | 1.11 | uM | LJP6 | 1 | K15 | 72 | hr | 513 | 2657 | 10401 | 0.2555 | 0.2168 |
| MCF 10A | NVP-TAE684 | 1.11 | uM | LJP6 | 2 | K15 | 72 | hr | 513 | 2496 | 10401 | 0.2400 | 0.2005 |
| MCF 10A | NVP-TAE684 | 1.11 | uM | LJP6 | 3 | K15 | 72 | hr | 513 | 2042 | 10401 | 0.1963 | 0.1546 |
| MCF 10A | Palbociclib | 1.11 | uM | LJP6 | 1 | E15 | 72 | hr | 513 | 3784 | 10401 | 0.3638 | 0.3308 |
| MCF 10A | Palbociclib | 1.11 | uM | LJP6 | 2 | E15 | 72 | hr | 513 | 3839 | 10401 | 0.3691 | 0.3363 |
| MCF 10A | Palbociclib | 1.11 | uM | LJP6 | 3 | E15 | 72 | hr | 513 | 3685 | 10401 | 0.3543 | 0.3208 |