LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF 10A XMD16-144
3.33
uM
LJP5
 3
M08
 72
hr
 513 1133 10401 0.1089 0.0627
MCF 10A Brivanib
3.33
uM
LJP5
 1
P14
 72
hr
 513 3961 10401 0.3808 0.3487
MCF 10A Brivanib
3.33
uM
LJP5
 2
P14
 72
hr
 513 4977 10401 0.4785 0.4514
MCF 10A Brivanib
3.33
uM
LJP5
 3
P14
 72
hr
 513 4986 10401 0.4794 0.4523
MCF 10A Buparlisib
3.33
uM
LJP5
 1
H02
 72
hr
 513 318 10401 0.0306 -0.0198
MCF 10A Buparlisib
3.33
uM
LJP5
 2
H02
 72
hr
 513 357 10401 0.0343 -0.0158
MCF 10A Buparlisib
3.33
uM
LJP5
 3
H02
 72
hr
 513 483 10401 0.0464 -0.0031
MCF 10A BX-912
3.33
uM
LJP5
 1
L20
 72
hr
 513 1282 10401 0.1233 0.0777
MCF 10A BX-912
3.33
uM
LJP5
 2
L20
 72
hr
 513 1387 10401 0.1334 0.0884
MCF 10A BX-912
3.33
uM
LJP5
 3
L20
 72
hr
 513 1310 10401 0.1260 0.0806
MCF 10A Canertinib
3.33
uM
LJP6
 1
H08
 72
hr
 513 761 10401 0.0732 0.0250
MCF 10A Canertinib
3.33
uM
LJP6
 2
H08
 72
hr
 513 680 10401 0.0654 0.0169
MCF 10A Canertinib
3.33
uM
LJP6
 3
H08
 72
hr
 513 642 10401 0.0617 0.0130
MCF 10A Celastrol
3.33
uM
LJP6
 1
G08
 72
hr
 513 369 10401 0.0355 -0.0146
MCF 10A Celastrol
3.33
uM
LJP6
 2
G08
 72
hr
 513 471 10401 0.0453 -0.0043
MCF 10A Celastrol
3.33
uM
LJP6
 3
G08
 72
hr
 513 511 10401 0.0491 -0.0002
MCF 10A CGP60474
3.33
uM
LJP5
 1
F02
 72
hr
 513 629 10401 0.0605 0.0117
MCF 10A CGP60474
3.33
uM
LJP5
 2
F02
 72
hr
 513 699 10401 0.0672 0.0188
MCF 10A CGP60474
3.33
uM
LJP5
 3
F02
 72
hr
 513 670 10401 0.0644 0.0158
MCF 10A CGP60474
3.33
uM
LJP6
 1
G02
 72
hr
 513 330 10401 0.0317 -0.0185
MCF 10A CGP60474
3.33
uM
LJP6
 2
G02
 72
hr
 513 392 10401 0.0377 -0.0123
MCF 10A CGP60474
3.33
uM
LJP6
 3
G02
 72
hr
 513 730 10401 0.0702 0.0219
MCF 10A CHIR-99021
3.33
uM
LJP6
 1
P14
 72
hr
 513 6494 10401 0.6244 0.6049
MCF 10A CHIR-99021
3.33
uM
LJP6
 2
P14
 72
hr
 513 5837 10401 0.5612 0.5384
MCF 10A CHIR-99021
3.33
uM
LJP6
 3
P14
 72
hr
 513 6015 10401 0.5783 0.5564