LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF 10A Erlotinib
3.33
uM
LJP5
 2
M20
 72
hr
 513 697 10401 0.0670 0.0186
MCF 10A Erlotinib
3.33
uM
LJP5
 3
M20
 72
hr
 513 688 10401 0.0661 0.0177
MCF 10A Foretinib
3.33
uM
LJP5
 1
H08
 72
hr
 513 1140 10401 0.1096 0.0634
MCF 10A Foretinib
3.33
uM
LJP5
 2
H08
 72
hr
 513 1156 10401 0.1111 0.0650
MCF 10A Foretinib
3.33
uM
LJP5
 3
H08
 72
hr
 513 1146 10401 0.1102 0.0640
MCF 10A R406
3.33
uM
LJP6
 1
C14
 72
hr
 513 4581 10401 0.4404 0.4114
MCF 10A R406
3.33
uM
LJP6
 2
C14
 72
hr
 513 5335 10401 0.5129 0.4876
MCF 10A R406
3.33
uM
LJP6
 3
C14
 72
hr
 513 5986 10401 0.5755 0.5535
MCF 10A Pictilisib
3.33
uM
LJP6
 1
D20
 72
hr
 513 948 10401 0.0911 0.0440
MCF 10A Pictilisib
3.33
uM
LJP6
 2
D20
 72
hr
 513 1200 10401 0.1154 0.0694
MCF 10A Pictilisib
3.33
uM
LJP6
 3
D20
 72
hr
 513 1165 10401 0.1120 0.0659
MCF 10A Gefitinib
3.33
uM
LJP6
 1
N08
 72
hr
 513 919 10401 0.0884 0.0410
MCF 10A Gefitinib
3.33
uM
LJP6
 2
N08
 72
hr
 513 760 10401 0.0731 0.0249
MCF 10A Gefitinib
3.33
uM
LJP6
 3
N08
 72
hr
 513 680 10401 0.0654 0.0169
MCF 10A Geldanamycin
3.33
uM
LJP5
 1
O02
 72
hr
 513 400 10401 0.0385 -0.0115
MCF 10A Geldanamycin
3.33
uM
LJP5
 2
O02
 72
hr
 513 329 10401 0.0316 -0.0186
MCF 10A Geldanamycin
3.33
uM
LJP5
 3
O02
 72
hr
 513 439 10401 0.0422 -0.0075
MCF 10A Geldanamycin
3.33
uM
LJP6
 1
O02
 72
hr
 513 366 10401 0.0352 -0.0149
MCF 10A Geldanamycin
3.33
uM
LJP6
 2
O02
 72
hr
 513 375 10401 0.0361 -0.0140
MCF 10A Geldanamycin
3.33
uM
LJP6
 3
O02
 72
hr
 513 438 10401 0.0421 -0.0076
MCF 10A GSK1059615
3.33
uM
LJP5
 1
E02
 72
hr
 513 275 10401 0.0264 -0.0241
MCF 10A GSK1059615
3.33
uM
LJP5
 2
E02
 72
hr
 513 403 10401 0.0387 -0.0112
MCF 10A GSK1059615
3.33
uM
LJP5
 3
E02
 72
hr
 513 368 10401 0.0354 -0.0147
MCF 10A GSK1059615
3.33
uM
LJP6
 1
C02
 72
hr
 513 417 10401 0.0401 -0.0097
MCF 10A GSK1059615
3.33
uM
LJP6
 2
C02
 72
hr
 513 448 10401 0.0431 -0.0066