LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Buparlisib | 0.37 | uM | LJP5 | 2 | H04 | 72 | hr | 1476 | 1585 | 3694 | 0.4291 | 0.0488 |
| SK-BR-3 | Buparlisib | 0.37 | uM | LJP5 | 3 | H04 | 72 | hr | 1476 | 1683 | 3694 | 0.4556 | 0.0930 |
| SK-BR-3 | BX-912 | 0.37 | uM | LJP5 | 1 | L22 | 72 | hr | 1476 | 1690 | 3694 | 0.4575 | 0.0962 |
| SK-BR-3 | BX-912 | 0.37 | uM | LJP5 | 2 | L22 | 72 | hr | 1476 | 1780 | 3694 | 0.4819 | 0.1368 |
| SK-BR-3 | BX-912 | 0.37 | uM | LJP5 | 3 | L22 | 72 | hr | 1476 | 1744 | 3694 | 0.4721 | 0.1205 |
| SK-BR-3 | Canertinib | 0.37 | uM | LJP6 | 1 | H10 | 72 | hr | 1476 | 1604 | 3694 | 0.4342 | 0.0574 |
| SK-BR-3 | Canertinib | 0.37 | uM | LJP6 | 2 | H10 | 72 | hr | 1476 | 1476 | 3694 | 0.3996 | -0.0003 |
| SK-BR-3 | Canertinib | 0.37 | uM | LJP6 | 3 | H10 | 72 | hr | 1476 | 1462 | 3694 | 0.3958 | -0.0066 |
| SK-BR-3 | Celastrol | 0.37 | uM | LJP6 | 1 | G10 | 72 | hr | 1476 | 1202 | 3694 | 0.3254 | -0.1239 |
| SK-BR-3 | Celastrol | 0.37 | uM | LJP6 | 2 | G10 | 72 | hr | 1476 | 1563 | 3694 | 0.4231 | 0.0389 |
| SK-BR-3 | Celastrol | 0.37 | uM | LJP6 | 3 | G10 | 72 | hr | 1476 | 1507 | 3694 | 0.4080 | 0.0137 |
| SK-BR-3 | CGP60474 | 0.37 | uM | LJP5 | 1 | F04 | 72 | hr | 1476 | 1332 | 3694 | 0.3606 | -0.0653 |
| SK-BR-3 | CGP60474 | 0.37 | uM | LJP5 | 2 | F04 | 72 | hr | 1476 | 1272 | 3694 | 0.3443 | -0.0923 |
| SK-BR-3 | CGP60474 | 0.37 | uM | LJP5 | 3 | F04 | 72 | hr | 1476 | 1538 | 3694 | 0.4164 | 0.0276 |
| SK-BR-3 | CGP60474 | 0.37 | uM | LJP6 | 1 | G04 | 72 | hr | 1476 | 1000 | 3694 | 0.2707 | -0.2150 |
| SK-BR-3 | CGP60474 | 0.37 | uM | LJP6 | 2 | G04 | 72 | hr | 1476 | 1012 | 3694 | 0.2740 | -0.2096 |
| SK-BR-3 | CGP60474 | 0.37 | uM | LJP6 | 3 | G04 | 72 | hr | 1476 | 985 | 3694 | 0.2666 | -0.2218 |
| SK-BR-3 | CHIR-99021 | 0.37 | uM | LJP6 | 1 | P16 | 72 | hr | 1476 | 2821 | 3694 | 0.7637 | 0.6063 |
| SK-BR-3 | CHIR-99021 | 0.37 | uM | LJP6 | 2 | P16 | 72 | hr | 1476 | 3060 | 3694 | 0.8284 | 0.7141 |
| SK-BR-3 | CHIR-99021 | 0.37 | uM | LJP6 | 3 | P16 | 72 | hr | 1476 | 2956 | 3694 | 0.8002 | 0.6671 |
| SK-BR-3 | CP724714 | 0.37 | uM | LJP5 | 1 | A10 | 72 | hr | 1476 | 1912 | 3694 | 0.5176 | 0.1963 |
| SK-BR-3 | CP724714 | 0.37 | uM | LJP5 | 2 | A10 | 72 | hr | 1476 | 1877 | 3694 | 0.5081 | 0.1805 |
| SK-BR-3 | CP724714 | 0.37 | uM | LJP5 | 3 | A10 | 72 | hr | 1476 | 1604 | 3694 | 0.4342 | 0.0574 |
| SK-BR-3 | CP466722 | 0.37 | uM | LJP5 | 1 | I10 | 72 | hr | 1476 | 3947 | 3694 | 1.0685 | 1.1141 |
| SK-BR-3 | CP466722 | 0.37 | uM | LJP5 | 2 | I10 | 72 | hr | 1476 | 3559 | 3694 | 0.9634 | 0.9391 |