LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | JW-7-24-1 | 0.12 | uM | LJP6 | 1 | B23 | 72 | hr | 1476 | 2676 | 3694 | 0.7244 | 0.5409 |
| SK-BR-3 | JW-7-24-1 | 0.12 | uM | LJP6 | 2 | B23 | 72 | hr | 1476 | 3009 | 3694 | 0.8146 | 0.6911 |
| SK-BR-3 | JW-7-24-1 | 0.12 | uM | LJP6 | 3 | B23 | 72 | hr | 1476 | 2977 | 3694 | 0.8059 | 0.6766 |
| SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 1 | M23 | 72 | hr | 1476 | 1513 | 3694 | 0.4096 | 0.0164 |
| SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 2 | M23 | 72 | hr | 1476 | 1510 | 3694 | 0.4088 | 0.0150 |
| SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 3 | M23 | 72 | hr | 1476 | 1555 | 3694 | 0.4210 | 0.0353 |
| SK-BR-3 | LDN-193189 | 0.12 | uM | LJP5 | 1 | G05 | 72 | hr | 1476 | 4175 | 3694 | 1.1302 | 1.2169 |
| SK-BR-3 | LDN-193189 | 0.12 | uM | LJP5 | 2 | G05 | 72 | hr | 1476 | 4046 | 3694 | 1.0953 | 1.1587 |
| SK-BR-3 | LDN-193189 | 0.12 | uM | LJP5 | 3 | G05 | 72 | hr | 1476 | 4353 | 3694 | 1.1784 | 1.2972 |
| SK-BR-3 | Linifanib | 0.12 | uM | LJP6 | 1 | J11 | 72 | hr | 1476 | 3470 | 3694 | 0.9394 | 0.8990 |
| SK-BR-3 | Linifanib | 0.12 | uM | LJP6 | 2 | J11 | 72 | hr | 1476 | 3991 | 3694 | 1.0804 | 1.1339 |
| SK-BR-3 | Linifanib | 0.12 | uM | LJP6 | 3 | J11 | 72 | hr | 1476 | 4153 | 3694 | 1.1242 | 1.2070 |
| SK-BR-3 | Linsitinib | 0.12 | uM | LJP5 | 1 | O23 | 72 | hr | 1476 | 2933 | 3694 | 0.7940 | 0.6568 |
| SK-BR-3 | Linsitinib | 0.12 | uM | LJP5 | 2 | O23 | 72 | hr | 1476 | 3047 | 3694 | 0.8248 | 0.7082 |
| SK-BR-3 | Linsitinib | 0.12 | uM | LJP5 | 3 | O23 | 72 | hr | 1476 | 2812 | 3694 | 0.7612 | 0.6022 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP5 | 1 | C23 | 72 | hr | 1476 | 1604 | 3694 | 0.4342 | 0.0574 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP5 | 2 | C23 | 72 | hr | 1476 | 1583 | 3694 | 0.4285 | 0.0479 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP5 | 3 | C23 | 72 | hr | 1476 | 1603 | 3694 | 0.4339 | 0.0570 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP6 | 1 | C23 | 72 | hr | 1476 | 1530 | 3694 | 0.4142 | 0.0240 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP6 | 2 | C23 | 72 | hr | 1476 | 1546 | 3694 | 0.4185 | 0.0312 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP6 | 3 | C23 | 72 | hr | 1476 | 1519 | 3694 | 0.4112 | 0.0191 |
| SK-BR-3 | MK2206 | 0.12 | uM | LJP6 | 1 | F05 | 72 | hr | 1476 | 2811 | 3694 | 0.7610 | 0.6018 |
| SK-BR-3 | MK2206 | 0.12 | uM | LJP6 | 2 | F05 | 72 | hr | 1476 | 2907 | 3694 | 0.7869 | 0.6451 |
| SK-BR-3 | MK2206 | 0.12 | uM | LJP6 | 3 | F05 | 72 | hr | 1476 | 3122 | 3694 | 0.8451 | 0.7420 |
| SK-BR-3 | Neratinib | 0.12 | uM | LJP5 | 1 | A17 | 72 | hr | 1476 | 1405 | 3694 | 0.3803 | -0.0323 |