LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | A443654 | 0.37 | uM | LJP6 | 1 | I22 | 72 | hr | 1476 | 1079 | 3694 | 0.2921 | -0.1794 |
| SK-BR-3 | A443654 | 0.37 | uM | LJP6 | 2 | I22 | 72 | hr | 1476 | 1060 | 3694 | 0.2870 | -0.1879 |
| SK-BR-3 | A443654 | 0.37 | uM | LJP6 | 3 | I22 | 72 | hr | 1476 | 1216 | 3694 | 0.3292 | -0.1176 |
| SK-BR-3 | OSI-027 | 0.37 | uM | LJP6 | 1 | E10 | 72 | hr | 1476 | 1731 | 3694 | 0.4686 | 0.1147 |
| SK-BR-3 | OSI-027 | 0.37 | uM | LJP6 | 2 | E10 | 72 | hr | 1476 | 1957 | 3694 | 0.5298 | 0.2166 |
| SK-BR-3 | OSI-027 | 0.37 | uM | LJP6 | 3 | E10 | 72 | hr | 1476 | 2040 | 3694 | 0.5522 | 0.2540 |
| SK-BR-3 | XMD11-85h | 0.37 | uM | LJP6 | 1 | P22 | 72 | hr | 1476 | 3020 | 3694 | 0.8175 | 0.6960 |
| SK-BR-3 | XMD11-85h | 0.37 | uM | LJP6 | 2 | P22 | 72 | hr | 1476 | 3026 | 3694 | 0.8192 | 0.6987 |
| SK-BR-3 | XMD11-85h | 0.37 | uM | LJP6 | 3 | P22 | 72 | hr | 1476 | 2938 | 3694 | 0.7953 | 0.6590 |
| SK-BR-3 | HG-6-64-01 | 0.37 | uM | LJP6 | 1 | M04 | 72 | hr | 1476 | 3133 | 3694 | 0.8481 | 0.7470 |
| SK-BR-3 | HG-6-64-01 | 0.37 | uM | LJP6 | 2 | M04 | 72 | hr | 1476 | 3388 | 3694 | 0.9172 | 0.8620 |
| SK-BR-3 | HG-6-64-01 | 0.37 | uM | LJP6 | 3 | M04 | 72 | hr | 1476 | 3237 | 3694 | 0.8763 | 0.7939 |
| SK-BR-3 | WH-4-025 | 0.37 | uM | LJP5 | 1 | O10 | 72 | hr | 1476 | 3671 | 3694 | 0.9938 | 0.9896 |
| SK-BR-3 | WH-4-025 | 0.37 | uM | LJP5 | 2 | O10 | 72 | hr | 1476 | 3091 | 3694 | 0.8368 | 0.7280 |
| SK-BR-3 | WH-4-025 | 0.37 | uM | LJP5 | 3 | O10 | 72 | hr | 1476 | 3202 | 3694 | 0.8668 | 0.7781 |
| SK-BR-3 | WZ-4-145 | 0.37 | uM | LJP6 | 1 | J22 | 72 | hr | 1476 | 1986 | 3694 | 0.5376 | 0.2297 |
| SK-BR-3 | WZ-4-145 | 0.37 | uM | LJP6 | 2 | J22 | 72 | hr | 1476 | 2180 | 3694 | 0.5901 | 0.3172 |
| SK-BR-3 | WZ-4-145 | 0.37 | uM | LJP6 | 3 | J22 | 72 | hr | 1476 | 2022 | 3694 | 0.5474 | 0.2459 |
| SK-BR-3 | XMD16-144 | 0.37 | uM | LJP5 | 1 | M10 | 72 | hr | 1476 | 1549 | 3694 | 0.4193 | 0.0326 |
| SK-BR-3 | XMD16-144 | 0.37 | uM | LJP5 | 2 | M10 | 72 | hr | 1476 | 1430 | 3694 | 0.3871 | -0.0211 |
| SK-BR-3 | XMD16-144 | 0.37 | uM | LJP5 | 3 | M10 | 72 | hr | 1476 | 1456 | 3694 | 0.3942 | -0.0093 |
| SK-BR-3 | Brivanib | 0.37 | uM | LJP5 | 1 | P16 | 72 | hr | 1476 | 3019 | 3694 | 0.8173 | 0.6956 |
| SK-BR-3 | Brivanib | 0.37 | uM | LJP5 | 2 | P16 | 72 | hr | 1476 | 3110 | 3694 | 0.8419 | 0.7366 |
| SK-BR-3 | Brivanib | 0.37 | uM | LJP5 | 3 | P16 | 72 | hr | 1476 | 2918 | 3694 | 0.7899 | 0.6500 |
| SK-BR-3 | Buparlisib | 0.37 | uM | LJP5 | 1 | H04 | 72 | hr | 1476 | 1766 | 3694 | 0.4781 | 0.1305 |