LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 CP466722
0.37
uM
LJP5
 3
I10
 72
hr
 1476 3815 3694 1.0327 1.0545
SK-BR-3 Crizotinib
0.37
uM
LJP5
 1
A22
 72
hr
 1476 2613 3694 0.7074 0.5125
SK-BR-3 Crizotinib
0.37
uM
LJP5
 2
A22
 72
hr
 1476 2875 3694 0.7783 0.6306
SK-BR-3 Crizotinib
0.37
uM
LJP5
 3
A22
 72
hr
 1476 2987 3694 0.8086 0.6811
SK-BR-3 Momelotinib
0.37
uM
LJP5
 1
P10
 72
hr
 1476 3055 3694 0.8270 0.7118
SK-BR-3 Momelotinib
0.37
uM
LJP5
 2
P10
 72
hr
 1476 2950 3694 0.7986 0.6644
SK-BR-3 Momelotinib
0.37
uM
LJP5
 3
P10
 72
hr
 1476 2868 3694 0.7764 0.6275
SK-BR-3 Dasatinib
0.37
uM
LJP5
 1
D04
 72
hr
 1476 3397 3694 0.9196 0.8660
SK-BR-3 Dasatinib
0.37
uM
LJP5
 2
D04
 72
hr
 1476 3834 3694 1.0379 1.0631
SK-BR-3 Dasatinib
0.37
uM
LJP5
 3
D04
 72
hr
 1476 3565 3694 0.9651 0.9418
SK-BR-3 Dasatinib
0.37
uM
LJP6
 1
I04
 72
hr
 1476 3536 3694 0.9572 0.9287
SK-BR-3 Dasatinib
0.37
uM
LJP6
 2
I04
 72
hr
 1476 3612 3694 0.9778 0.9630
SK-BR-3 Dasatinib
0.37
uM
LJP6
 3
I04
 72
hr
 1476 3753 3694 1.0160 1.0266
SK-BR-3 Dovitinib
0.37
uM
LJP5
 1
E22
 72
hr
 1476 2438 3694 0.6600 0.4335
SK-BR-3 Dovitinib
0.37
uM
LJP5
 2
E22
 72
hr
 1476 2359 3694 0.6386 0.3979
SK-BR-3 Dovitinib
0.37
uM
LJP5
 3
E22
 72
hr
 1476 2738 3694 0.7412 0.5688
SK-BR-3 Enzastaurin
0.37
uM
LJP5
 1
D16
 72
hr
 1476 3942 3694 1.0671 1.1118
SK-BR-3 Enzastaurin
0.37
uM
LJP5
 2
D16
 72
hr
 1476 4143 3694 1.1215 1.2025
SK-BR-3 Enzastaurin
0.37
uM
LJP5
 3
D16
 72
hr
 1476 4183 3694 1.1324 1.2205
SK-BR-3 Erlotinib
0.37
uM
LJP5
 1
M22
 72
hr
 1476 3586 3694 0.9708 0.9513
SK-BR-3 Erlotinib
0.37
uM
LJP5
 2
M22
 72
hr
 1476 3211 3694 0.8692 0.7822
SK-BR-3 Erlotinib
0.37
uM
LJP5
 3
M22
 72
hr
 1476 3479 3694 0.9418 0.9030
SK-BR-3 Foretinib
0.37
uM
LJP5
 1
H10
 72
hr
 1476 1594 3694 0.4315 0.0529
SK-BR-3 Foretinib
0.37
uM
LJP5
 2
H10
 72
hr
 1476 1555 3694 0.4210 0.0353
SK-BR-3 Foretinib
0.37
uM
LJP5
 3
H10
 72
hr
 1476 1427 3694 0.3863 -0.0224