LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 XL147
0.37
uM
LJP5
 2
G10
 72
hr
 868 3689 3486 1.0581 1.0774
MDA-MB-231 XL147
0.37
uM
LJP5
 3
G10
 72
hr
 868 3682 3486 1.0561 1.0747
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 1
D10
 72
hr
 868 2563 3486 0.7351 0.6473
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 2
D10
 72
hr
 868 2255 3486 0.6468 0.5297
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 3
D10
 72
hr
 868 2336 3486 0.6700 0.5606
MDA-MB-231 Selumetinib
0.37
uM
LJP6
 1
M10
 72
hr
 868 1895 3486 0.5435 0.3922
MDA-MB-231 Selumetinib
0.37
uM
LJP6
 2
M10
 72
hr
 868 2110 3486 0.6052 0.4743
MDA-MB-231 Selumetinib
0.37
uM
LJP6
 3
M10
 72
hr
 868 1917 3486 0.5499 0.4006
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 1
L16
 72
hr
 868 2708 3486 0.7767 0.7027
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 2
L16
 72
hr
 868 3127 3486 0.8969 0.8627
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 3
L16
 72
hr
 868 3089 3486 0.8860 0.8482
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 1
B10
 72
hr
 868 2995 3486 0.8591 0.8123
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 2
B10
 72
hr
 868 2771 3486 0.7948 0.7268
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 3
B10
 72
hr
 868 2816 3486 0.8077 0.7440
MDA-MB-231 SU11274
0.37
uM
LJP5
 1
J10
 72
hr
 868 3423 3486 0.9818 0.9758
MDA-MB-231 SU11274
0.37
uM
LJP5
 2
J10
 72
hr
 868 3730 3486 1.0699 1.0930
MDA-MB-231 SU11274
0.37
uM
LJP5
 3
J10
 72
hr
 868 3681 3486 1.0558 1.0743
MDA-MB-231 Fedratinib
0.37
uM
LJP5
 1
L04
 72
hr
 868 3074 3486 0.8817 0.8425
MDA-MB-231 Fedratinib
0.37
uM
LJP5
 2
L04
 72
hr
 868 3193 3486 0.9159 0.8879
MDA-MB-231 Fedratinib
0.37
uM
LJP5
 3
L04
 72
hr
 868 3146 3486 0.9024 0.8700
MDA-MB-231 TGX221
0.37
uM
LJP5
 1
H22
 72
hr
 868 2418 3486 0.6936 0.5920
MDA-MB-231 TGX221
0.37
uM
LJP5
 2
H22
 72
hr
 868 2591 3486 0.7432 0.6580
MDA-MB-231 TGX221
0.37
uM
LJP5
 3
H22
 72
hr
 868 2656 3486 0.7618 0.6829
MDA-MB-231 Torin1
0.37
uM
LJP6
 1
O16
 72
hr
 868 1458 3486 0.4182 0.2253
MDA-MB-231 Torin1
0.37
uM
LJP6
 2
O16
 72
hr
 868 1558 3486 0.4469 0.2635