LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Torin1
0.37
uM
LJP6
 3
O16
 72
hr
 868 1542 3486 0.4423 0.2574
MDA-MB-231 Torin2
0.37
uM
LJP5
 1
I22
 72
hr
 868 1039 3486 0.2980 0.0653
MDA-MB-231 Torin2
0.37
uM
LJP5
 2
I22
 72
hr
 868 1122 3486 0.3218 0.0970
MDA-MB-231 Torin2
0.37
uM
LJP5
 3
I22
 72
hr
 868 1136 3486 0.3258 0.1023
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 1
B16
 72
hr
 868 1129 3486 0.3238 0.0996
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 2
B16
 72
hr
 868 1070 3486 0.3069 0.0771
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 3
B16
 72
hr
 868 1123 3486 0.3221 0.0973
MDA-MB-231 Trametinib
0.37
uM
LJP5
 1
P22
 72
hr
 868 1249 3486 0.3583 0.1455
MDA-MB-231 Trametinib
0.37
uM
LJP5
 2
P22
 72
hr
 868 1128 3486 0.3235 0.0993
MDA-MB-231 Trametinib
0.37
uM
LJP5
 3
P22
 72
hr
 868 1222 3486 0.3505 0.1352
MDA-MB-231 TWS119
0.37
uM
LJP5
 1
M04
 72
hr
 868 3409 3486 0.9778 0.9704
MDA-MB-231 TWS119
0.37
uM
LJP5
 2
M04
 72
hr
 868 3623 3486 1.0392 1.0522
MDA-MB-231 TWS119
0.37
uM
LJP5
 3
M04
 72
hr
 868 3360 3486 0.9638 0.9517
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 1
C16
 72
hr
 868 3209 3486 0.9204 0.8941
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 2
C16
 72
hr
 868 3289 3486 0.9434 0.9246
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 3
C16
 72
hr
 868 3243 3486 0.9302 0.9070
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 1
G16
 72
hr
 868 2291 3486 0.6571 0.5434
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 2
G16
 72
hr
 868 2231 3486 0.6399 0.5205
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 3
G16
 72
hr
 868 2079 3486 0.5963 0.4625
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 1
G16
 72
hr
 868 1818 3486 0.5215 0.3628
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 2
G16
 72
hr
 868 1999 3486 0.5734 0.4319
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 3
G16
 72
hr
 868 1939 3486 0.5562 0.4090
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 868 1758 3486 0.5043 0.3399
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 868 1913 3486 0.5487 0.3991
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 868 1948 3486 0.5587 0.4124