LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 WZ3105
0.37
uM
LJP5
 1
D22
 72
hr
 868 671 3486 0.1925 -0.0753
MDA-MB-231 WZ3105
0.37
uM
LJP5
 2
D22
 72
hr
 868 789 3486 0.2263 -0.0302
MDA-MB-231 WZ3105
0.37
uM
LJP5
 3
D22
 72
hr
 868 745 3486 0.2137 -0.0470
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 1
P10
 72
hr
 868 1803 3486 0.5172 0.3571
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 2
P10
 72
hr
 868 2027 3486 0.5814 0.4426
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 3
P10
 72
hr
 868 1967 3486 0.5642 0.4197
MDA-MB-231 Y39983
0.37
uM
LJP6
 1
P04
 72
hr
 868 2402 3486 0.6890 0.5858
MDA-MB-231 Y39983
0.37
uM
LJP6
 2
P04
 72
hr
 868 3045 3486 0.8734 0.8314
MDA-MB-231 Y39983
0.37
uM
LJP6
 3
P04
 72
hr
 868 3098 3486 0.8886 0.8517
MDA-MB-231 YM 201636
0.37
uM
LJP5
 1
N10
 72
hr
 868 2924 3486 0.8387 0.7852
MDA-MB-231 YM 201636
0.37
uM
LJP5
 2
N10
 72
hr
 868 3466 3486 0.9942 0.9922
MDA-MB-231 YM 201636
0.37
uM
LJP5
 3
N10
 72
hr
 868 3038 3486 0.8714 0.8287
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 1
M16
 72
hr
 868 2710 3486 0.7773 0.7035
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 2
M16
 72
hr
 868 2753 3486 0.7896 0.7199
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 3
M16
 72
hr
 868 2724 3486 0.7813 0.7088
MDA-MB-231 Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 868 2455 3486 0.7042 0.6061
MDA-MB-231 Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 868 2627 3486 0.7535 0.6718
MDA-MB-231 Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 868 2797 3486 0.8023 0.7367
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 1
B21
 72
hr
 868 2485 3486 0.7128 0.6175
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 2
B21
 72
hr
 868 2650 3486 0.7601 0.6806
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 3
B21
 72
hr
 868 2700 3486 0.7744 0.6997
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 1
A15
 72
hr
 868 700 3486 0.2008 -0.0642
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 2
A15
 72
hr
 868 661 3486 0.1896 -0.0791
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 3
A15
 72
hr
 868 616 3486 0.1767 -0.0963
MDA-MB-231 AT-7519
1.11
uM
LJP6
 1
K03
 72
hr
 868 590 3486 0.1692 -0.1062