LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 BI-2536
0.37
uM
LJP6
 1
D16
 72
hr
 868 1355 3486 0.3887 0.1860
MDA-MB-231 BI-2536
0.37
uM
LJP6
 2
D16
 72
hr
 868 1091 3486 0.3129 0.0851
MDA-MB-231 BI-2536
0.37
uM
LJP6
 3
D16
 72
hr
 868 1066 3486 0.3058 0.0756
MDA-MB-231 BMS345541
0.37
uM
LJP6
 1
D04
 72
hr
 868 3443 3486 0.9876 0.9834
MDA-MB-231 BMS345541
0.37
uM
LJP6
 2
D04
 72
hr
 868 3191 3486 0.9153 0.8872
MDA-MB-231 BMS345541
0.37
uM
LJP6
 3
D04
 72
hr
 868 3152 3486 0.9041 0.8723
MDA-MB-231 SNS-032
0.37
uM
LJP6
 1
H16
 72
hr
 868 780 3486 0.2237 -0.0337
MDA-MB-231 SNS-032
0.37
uM
LJP6
 2
H16
 72
hr
 868 765 3486 0.2194 -0.0394
MDA-MB-231 SNS-032
0.37
uM
LJP6
 3
H16
 72
hr
 868 770 3486 0.2209 -0.0375
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 1
K22
 72
hr
 868 1868 3486 0.5358 0.3819
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 2
K22
 72
hr
 868 1924 3486 0.5519 0.4033
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 3
K22
 72
hr
 868 1849 3486 0.5304 0.3746
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 1
E16
 72
hr
 868 3622 3486 1.0389 1.0518
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 2
E16
 72
hr
 868 3251 3486 0.9325 0.9101
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 3
E16
 72
hr
 868 3876 3486 1.1117 1.1488
MDA-MB-231 SB590885
0.37
uM
LJP5
 1
L16
 72
hr
 868 2508 3486 0.7194 0.6263
MDA-MB-231 SB590885
0.37
uM
LJP5
 2
L16
 72
hr
 868 3048 3486 0.8743 0.8326
MDA-MB-231 SB590885
0.37
uM
LJP5
 3
L16
 72
hr
 868 2760 3486 0.7917 0.7226
MDA-MB-231 PIK-93
0.37
uM
LJP5
 1
K16
 72
hr
 868 3580 3486 1.0268 1.0357
MDA-MB-231 PIK-93
0.37
uM
LJP5
 2
K16
 72
hr
 868 4267 3486 1.2239 1.2981
MDA-MB-231 PIK-93
0.37
uM
LJP5
 3
K16
 72
hr
 868 3360 3486 0.9638 0.9517
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 1
C10
 72
hr
 868 3421 3486 0.9812 0.9750
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 2
C10
 72
hr
 868 2761 3486 0.7919 0.7230
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 3
C10
 72
hr
 868 2910 3486 0.8347 0.7799
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 1
N04
 72
hr
 868 3156 3486 0.9052 0.8738