LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 WZ-4-145
0.12
uM
LJP6
 1
J23
 72
hr
 868 3020 3486 0.8662 0.8219
MDA-MB-231 WZ-4-145
0.12
uM
LJP6
 2
J23
 72
hr
 868 2900 3486 0.8318 0.7760
MDA-MB-231 WZ-4-145
0.12
uM
LJP6
 3
J23
 72
hr
 868 2885 3486 0.8275 0.7703
MDA-MB-231 XMD16-144
0.12
uM
LJP5
 1
M11
 72
hr
 868 1344 3486 0.3855 0.1818
MDA-MB-231 XMD16-144
0.12
uM
LJP5
 2
M11
 72
hr
 868 1310 3486 0.3758 0.1688
MDA-MB-231 XMD16-144
0.12
uM
LJP5
 3
M11
 72
hr
 868 1221 3486 0.3502 0.1348
MDA-MB-231 Brivanib
0.12
uM
LJP5
 1
P17
 72
hr
 868 2902 3486 0.8324 0.7768
MDA-MB-231 Brivanib
0.12
uM
LJP5
 2
P17
 72
hr
 868 2917 3486 0.8367 0.7825
MDA-MB-231 Brivanib
0.12
uM
LJP5
 3
P17
 72
hr
 868 2595 3486 0.7443 0.6596
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 1
H05
 72
hr
 868 3356 3486 0.9626 0.9502
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 2
H05
 72
hr
 868 3442 3486 0.9873 0.9830
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 3
H05
 72
hr
 868 3479 3486 0.9979 0.9972
MDA-MB-231 BX-912
0.12
uM
LJP5
 1
L23
 72
hr
 868 3019 3486 0.8659 0.8215
MDA-MB-231 BX-912
0.12
uM
LJP5
 2
L23
 72
hr
 868 3233 3486 0.9273 0.9032
MDA-MB-231 BX-912
0.12
uM
LJP5
 3
L23
 72
hr
 868 3265 3486 0.9365 0.9154
MDA-MB-231 Canertinib
0.12
uM
LJP6
 1
H11
 72
hr
 868 3084 3486 0.8846 0.8463
MDA-MB-231 Canertinib
0.12
uM
LJP6
 2
H11
 72
hr
 868 3660 3486 1.0498 1.0663
MDA-MB-231 Canertinib
0.12
uM
LJP6
 3
H11
 72
hr
 868 3407 3486 0.9772 0.9697
MDA-MB-231 Celastrol
0.12
uM
LJP6
 1
G11
 72
hr
 868 3621 3486 1.0386 1.0514
MDA-MB-231 Celastrol
0.12
uM
LJP6
 2
G11
 72
hr
 868 3659 3486 1.0495 1.0659
MDA-MB-231 Celastrol
0.12
uM
LJP6
 3
G11
 72
hr
 868 3926 3486 1.1261 1.1679
MDA-MB-231 CGP60474
0.12
uM
LJP5
 1
F05
 72
hr
 868 950 3486 0.2725 0.0313
MDA-MB-231 CGP60474
0.12
uM
LJP5
 2
F05
 72
hr
 868 903 3486 0.2590 0.0133
MDA-MB-231 CGP60474
0.12
uM
LJP5
 3
F05
 72
hr
 868 986 3486 0.2828 0.0450
MDA-MB-231 CGP60474
0.12
uM
LJP6
 1
G05
 72
hr
 868 775 3486 0.2223 -0.0356