LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Withaferin A
0.12
uM
LJP6
 2
G17
 72
hr
 868 3591 3486 1.0300 1.0400
MDA-MB-231 Withaferin A
0.12
uM
LJP6
 3
G17
 72
hr
 868 3417 3486 0.9801 0.9735
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 868 1859 3486 0.5332 0.3785
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 868 2147 3486 0.6158 0.4884
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 868 2219 3486 0.6365 0.5159
MDA-MB-231 WZ3105
0.12
uM
LJP5
 1
D23
 72
hr
 868 683 3486 0.1959 -0.0707
MDA-MB-231 WZ3105
0.12
uM
LJP5
 2
D23
 72
hr
 868 761 3486 0.2183 -0.0409
MDA-MB-231 WZ3105
0.12
uM
LJP5
 3
D23
 72
hr
 868 706 3486 0.2025 -0.0619
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 1
P11
 72
hr
 868 2641 3486 0.7575 0.6771
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 2
P11
 72
hr
 868 3280 3486 0.9408 0.9212
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 3
P11
 72
hr
 868 2809 3486 0.8057 0.7413
MDA-MB-231 Y39983
0.12
uM
LJP6
 1
P05
 72
hr
 868 2677 3486 0.7678 0.6909
MDA-MB-231 Y39983
0.12
uM
LJP6
 2
P05
 72
hr
 868 3417 3486 0.9801 0.9735
MDA-MB-231 Y39983
0.12
uM
LJP6
 3
P05
 72
hr
 868 3198 3486 0.9173 0.8899
MDA-MB-231 YM 201636
0.12
uM
LJP5
 1
N11
 72
hr
 868 2973 3486 0.8527 0.8039
MDA-MB-231 YM 201636
0.12
uM
LJP5
 2
N11
 72
hr
 868 3809 3486 1.0925 1.1232
MDA-MB-231 YM 201636
0.12
uM
LJP5
 3
N11
 72
hr
 868 3185 3486 0.9136 0.8849
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 1
M17
 72
hr
 868 3108 3486 0.8915 0.8555
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 2
M17
 72
hr
 868 3246 3486 0.9311 0.9082
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 3
M17
 72
hr
 868 3054 3486 0.8760 0.8349
MDA-MB-231 Afatinib
0.37
uM
LJP6
 1
G22
 72
hr
 868 2813 3486 0.8069 0.7428
MDA-MB-231 Afatinib
0.37
uM
LJP6
 2
G22
 72
hr
 868 3027 3486 0.8682 0.8245
MDA-MB-231 Afatinib
0.37
uM
LJP6
 3
G22
 72
hr
 868 2482 3486 0.7119 0.6164
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 1
B22
 72
hr
 868 2938 3486 0.8427 0.7906
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 2
B22
 72
hr
 868 3031 3486 0.8694 0.8261