LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Celastrol
0.04
uM
LJP6
 3
G12
 72
hr
 868 4037 3486 1.1579 1.2103
MDA-MB-231 CGP60474
0.04
uM
LJP5
 1
F06
 72
hr
 868 2448 3486 0.7022 0.6034
MDA-MB-231 CGP60474
0.04
uM
LJP5
 2
F06
 72
hr
 868 2520 3486 0.7228 0.6309
MDA-MB-231 CGP60474
0.04
uM
LJP5
 3
F06
 72
hr
 868 2226 3486 0.6385 0.5186
MDA-MB-231 CGP60474
0.04
uM
LJP6
 1
G06
 72
hr
 868 863 3486 0.2475 -0.0020
MDA-MB-231 CGP60474
0.04
uM
LJP6
 2
G06
 72
hr
 868 874 3486 0.2507 0.0022
MDA-MB-231 CGP60474
0.04
uM
LJP6
 3
G06
 72
hr
 868 873 3486 0.2504 0.0019
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 1
P18
 72
hr
 868 2997 3486 0.8596 0.8131
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 2
P18
 72
hr
 868 3257 3486 0.9342 0.9124
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 3
P18
 72
hr
 868 3019 3486 0.8659 0.8215
MDA-MB-231 CP724714
0.04
uM
LJP5
 1
A12
 72
hr
 868 2701 3486 0.7747 0.7000
MDA-MB-231 CP724714
0.04
uM
LJP5
 2
A12
 72
hr
 868 2414 3486 0.6924 0.5904
MDA-MB-231 CP724714
0.04
uM
LJP5
 3
A12
 72
hr
 868 2855 3486 0.8189 0.7589
MDA-MB-231 CP466722
0.04
uM
LJP5
 1
I12
 72
hr
 868 3687 3486 1.0575 1.0766
MDA-MB-231 CP466722
0.04
uM
LJP5
 2
I12
 72
hr
 868 3762 3486 1.0791 1.1053
MDA-MB-231 CP466722
0.04
uM
LJP5
 3
I12
 72
hr
 868 3997 3486 1.1465 1.1950
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 1
A24
 72
hr
 868 2398 3486 0.6878 0.5843
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 2
A24
 72
hr
 868 2728 3486 0.7825 0.7103
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 3
A24
 72
hr
 868 2323 3486 0.6663 0.5557
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 1
P12
 72
hr
 868 2489 3486 0.7139 0.6191
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 2
P12
 72
hr
 868 3139 3486 0.9004 0.8673
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 3
P12
 72
hr
 868 2688 3486 0.7710 0.6951
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 1
D06
 72
hr
 868 1762 3486 0.5054 0.3414
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 2
D06
 72
hr
 868 1489 3486 0.4271 0.2371
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 3
D06
 72
hr
 868 1694 3486 0.4859 0.3154