LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 1
I06
 72
hr
 868 719 3486 0.2062 -0.0570
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 2
I06
 72
hr
 868 771 3486 0.2212 -0.0371
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 3
I06
 72
hr
 868 841 3486 0.2412 -0.0104
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 1
E24
 72
hr
 868 2474 3486 0.7096 0.6133
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 2
E24
 72
hr
 868 2815 3486 0.8074 0.7436
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 3
E24
 72
hr
 868 2849 3486 0.8172 0.7566
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 1
D18
 72
hr
 868 3321 3486 0.9526 0.9368
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 2
D18
 72
hr
 868 3247 3486 0.9313 0.9086
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 3
D18
 72
hr
 868 3895 3486 1.1172 1.1561
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 1
M24
 72
hr
 868 2627 3486 0.7535 0.6718
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 2
M24
 72
hr
 868 3236 3486 0.9282 0.9044
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 3
M24
 72
hr
 868 2842 3486 0.8152 0.7539
MDA-MB-231 Foretinib
0.04
uM
LJP5
 1
H12
 72
hr
 868 3153 3486 0.9044 0.8727
MDA-MB-231 Foretinib
0.04
uM
LJP5
 2
H12
 72
hr
 868 3425 3486 0.9824 0.9766
MDA-MB-231 Foretinib
0.04
uM
LJP5
 3
H12
 72
hr
 868 3132 3486 0.8984 0.8646
MDA-MB-231 R406
0.04
uM
LJP6
 1
C18
 72
hr
 868 3676 3486 1.0544 1.0724
MDA-MB-231 R406
0.04
uM
LJP6
 2
C18
 72
hr
 868 3196 3486 0.9167 0.8891
MDA-MB-231 R406
0.04
uM
LJP6
 3
C18
 72
hr
 868 3413 3486 0.9790 0.9720
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 1
D24
 72
hr
 868 2450 3486 0.7027 0.6042
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 2
D24
 72
hr
 868 2473 3486 0.7093 0.6130
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 868 2580 3486 0.7400 0.6538
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 1
N12
 72
hr
 868 3985 3486 1.1430 1.1904
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 2
N12
 72
hr
 868 4155 3486 1.1918 1.2554
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 3
N12
 72
hr
 868 4060 3486 1.1645 1.2191
MDA-MB-231 Geldanamycin
0.04
uM
LJP5
 1
O06
 72
hr
 868 1176 3486 0.3373 0.1176