LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 868 2821 3486 0.8091 0.7459
MDA-MB-231 Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 868 2975 3486 0.8533 0.8047
MDA-MB-231 Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 868 3049 3486 0.8745 0.8329
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 1
B23
 72
hr
 868 2617 3486 0.7506 0.6680
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 2
B23
 72
hr
 868 2785 3486 0.7988 0.7321
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 3
B23
 72
hr
 868 2839 3486 0.8143 0.7527
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 1
A17
 72
hr
 868 622 3486 0.1784 -0.0940
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 2
A17
 72
hr
 868 610 3486 0.1750 -0.0986
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 3
A17
 72
hr
 868 675 3486 0.1936 -0.0738
MDA-MB-231 AT-7519
0.12
uM
LJP6
 1
K05
 72
hr
 868 2251 3486 0.6457 0.5282
MDA-MB-231 AT-7519
0.12
uM
LJP6
 2
K05
 72
hr
 868 2198 3486 0.6305 0.5079
MDA-MB-231 AT-7519
0.12
uM
LJP6
 3
K05
 72
hr
 868 2139 3486 0.6135 0.4854
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 1
J05
 72
hr
 868 2453 3486 0.7036 0.6053
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 2
J05
 72
hr
 868 2635 3486 0.7558 0.6748
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 3
J05
 72
hr
 868 2515 3486 0.7214 0.6290
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 1
I05
 72
hr
 868 3043 3486 0.8728 0.8307
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 2
I05
 72
hr
 868 3053 3486 0.8757 0.8345
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 3
I05
 72
hr
 868 3099 3486 0.8889 0.8520
MDA-MB-231 AZD7762
0.12
uM
LJP6
 1
L05
 72
hr
 868 1589 3486 0.4558 0.2753
MDA-MB-231 AZD7762
0.12
uM
LJP6
 2
L05
 72
hr
 868 1527 3486 0.4380 0.2517
MDA-MB-231 AZD7762
0.12
uM
LJP6
 3
L05
 72
hr
 868 1709 3486 0.4902 0.3212
MDA-MB-231 AZD8055
0.12
uM
LJP6
 1
A11
 72
hr
 868 1692 3486 0.4853 0.3147
MDA-MB-231 AZD8055
0.12
uM
LJP6
 2
A11
 72
hr
 868 1405 3486 0.4030 0.2051
MDA-MB-231 AZD8055
0.12
uM
LJP6
 3
A11
 72
hr
 868 1132 3486 0.3247 0.1008
MDA-MB-231 AZD8330
0.12
uM
LJP5
 1
G23
 72
hr
 868 1074 3486 0.3081 0.0786