Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20219)
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| Small Molecule | Cell Line | 2nd Drug | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Image | Measured Protein (Alexa Fluor 488) | Measured Protein Value (488) | Measured Protein (Alexa Fluor 568) | Measured Protein Value (568) | Measured Protein (Alexa Fluor 647) | Measured Protein Value (647) | Replicate | Plate Name | Plate Well |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| JNK-IN-8 | WM1552C | 0.3200 | uM | 24 | hr | | p-Histone H3(S10) | 249.08 | p-Rb(S807/S811) | 114.01 | p-S6(S235/S236 | 401.71 | 1 | WM1552C-signal2 | D5 | |
| JNK-IN-8 | WM1552C | 0.1280 | uM | 24 | hr | | p-Histone H3(S10) | 221.29 | p-Rb(S807/S811) | 114.21 | p-S6(S235/S236 | 384.84 | 1 | WM1552C-signal2 | D6 | |
| JNK-IN-8 | WM1552C | 0.0512 | uM | 24 | hr | | p-Histone H3(S10) | 173.20 | p-Rb(S807/S811) | 108.20 | p-S6(S235/S236 | 395.04 | 1 | WM1552C-signal2 | D7 | |
| JNK-IN-8 | WM1552C | 0.0205 | uM | 24 | hr | | p-Histone H3(S10) | 244.72 | p-Rb(S807/S811) | 115.35 | p-S6(S235/S236 | 425.96 | 1 | WM1552C-signal2 | D8 | |
| JNK-IN-8 | WM1552C | 0.0082 | uM | 24 | hr | | p-Histone H3(S10) | 184.24 | p-Rb(S807/S811) | 113.51 | p-S6(S235/S236 | 409.57 | 1 | WM1552C-signal2 | D9 | |
| JNK-IN-8 | WM1552C | 0.0033 | uM | 24 | hr | | p-Histone H3(S10) | 192.93 | p-Rb(S807/S811) | 112.08 | p-S6(S235/S236 | 409.76 | 2 | WM1552C-signal2 | E10 | |
| JNK-IN-8 | WM1552C | 0.0000 | uM | 24 | hr | | p-Histone H3(S10) | 200.92 | p-Rb(S807/S811) | 113.95 | p-S6(S235/S236 | 415.95 | 2 | WM1552C-signal2 | E11 | |
| JNK-IN-8 | WM1552C | 5.0000 | uM | 24 | hr | | p-Histone H3(S10) | 285.27 | p-Rb(S807/S811) | 112.32 | p-S6(S235/S236 | 447.61 | 2 | WM1552C-signal2 | E2 | |
| JNK-IN-8 | WM1552C | 2.0000 | uM | 24 | hr | | p-Histone H3(S10) | 228.44 | p-Rb(S807/S811) | 120.65 | p-S6(S235/S236 | 446.76 | 2 | WM1552C-signal2 | E3 | |
| JNK-IN-8 | WM1552C | 0.8000 | uM | 24 | hr | | p-Histone H3(S10) | 204.00 | p-Rb(S807/S811) | 111.59 | p-S6(S235/S236 | 385.25 | 2 | WM1552C-signal2 | E4 | |
| JNK-IN-8 | WM1552C | 0.3200 | uM | 24 | hr | | p-Histone H3(S10) | 238.67 | p-Rb(S807/S811) | 112.35 | p-S6(S235/S236 | 403.49 | 2 | WM1552C-signal2 | E5 | |
| JNK-IN-8 | WM1552C | 0.1280 | uM | 24 | hr | | p-Histone H3(S10) | 233.60 | p-Rb(S807/S811) | 115.43 | p-S6(S235/S236 | 404.08 | 2 | WM1552C-signal2 | E6 | |
| JNK-IN-8 | WM1552C | 0.0512 | uM | 24 | hr | | p-Histone H3(S10) | 202.01 | p-Rb(S807/S811) | 113.23 | p-S6(S235/S236 | 403.64 | 2 | WM1552C-signal2 | E7 | |
| JNK-IN-8 | WM1552C | 0.0205 | uM | 24 | hr | | p-Histone H3(S10) | 205.45 | p-Rb(S807/S811) | 114.75 | p-S6(S235/S236 | 404.26 | 2 | WM1552C-signal2 | E8 | |
| JNK-IN-8 | WM1552C | 0.0082 | uM | 24 | hr | | p-Histone H3(S10) | 179.59 | p-Rb(S807/S811) | 113.28 | p-S6(S235/S236 | 408.38 | 2 | WM1552C-signal2 | E9 | |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.0033 | uM | 24 | hr | | p-Histone H3(S10) | 211.27 | p-Rb(S807/S811) | 111.74 | p-S6(S235/S236 | 403.48 | 1 | WM1552C-signal2 | F10 |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.0000 | uM | 24 | hr | | p-Histone H3(S10) | 208.77 | p-Rb(S807/S811) | 116.05 | p-S6(S235/S236 | 419.33 | 1 | WM1552C-signal2 | F11 |
| Vemurafenib | WM1552C | JNK-IN-8 | 5.0000 | uM | 24 | hr | | p-Histone H3(S10) | 218.10 | p-Rb(S807/S811) | 64.53 | p-S6(S235/S236 | 16.11 | 1 | WM1552C-signal2 | F2 |
| Vemurafenib | WM1552C | JNK-IN-8 | 2.0000 | uM | 24 | hr | | p-Histone H3(S10) | 161.46 | p-Rb(S807/S811) | 50.96 | p-S6(S235/S236 | 229.99 | 1 | WM1552C-signal2 | F3 |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.8000 | uM | 24 | hr | | p-Histone H3(S10) | 158.30 | p-Rb(S807/S811) | 60.54 | p-S6(S235/S236 | 363.25 | 1 | WM1552C-signal2 | F4 |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.3200 | uM | 24 | hr | | p-Histone H3(S10) | 204.23 | p-Rb(S807/S811) | 70.93 | p-S6(S235/S236 | 342.80 | 1 | WM1552C-signal2 | F5 |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.1280 | uM | 24 | hr | | p-Histone H3(S10) | 165.37 | p-Rb(S807/S811) | 90.82 | p-S6(S235/S236 | 359.54 | 1 | WM1552C-signal2 | F6 |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.0512 | uM | 24 | hr | | p-Histone H3(S10) | 190.31 | p-Rb(S807/S811) | 96.89 | p-S6(S235/S236 | 375.87 | 1 | WM1552C-signal2 | F7 |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.0205 | uM | 24 | hr | | p-Histone H3(S10) | 217.43 | p-Rb(S807/S811) | 107.80 | p-S6(S235/S236 | 426.02 | 1 | WM1552C-signal2 | F8 |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.0082 | uM | 24 | hr | | p-Histone H3(S10) | 214.37 | p-Rb(S807/S811) | 82.91 | p-S6(S235/S236 | 372.87 | 1 | WM1552C-signal2 | F9 |